Overview

  • Product name
    Anti-BCL2L10 antibody - Aminoterminal end
    See all BCL2L10 primary antibodies
  • Description
    Rabbit polyclonal to BCL2L10 - Aminoterminal end
  • Specificity
    This antibody is specific for BCL2L10.
  • Tested applications
    Suitable for: ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A 16 amino acid peptide from near the amino terminus of human BCL2L10

  • Positive control
    • Jurkat cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab45412 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 10 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 23 kDa). High MW is probably due to post-translational modifications.

Target

  • Function
    Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK.
  • Tissue specificity
    Widely expressed in adult tissues. Preferentially expressed in lung, liver and kidney.
  • Sequence similarities
    Belongs to the Bcl-2 family.
  • Cellular localization
    Mitochondrion. Nucleus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Anti apoptotic protein NrH antibody
    • Anti-apoptotic protein NrH antibody
    • Apoptosis regulator Bcl B antibody
    • Apoptosis regulator Bcl-B antibody
    • B2L10_HUMAN antibody
    • BCL B antibody
    • Bcl-2-like protein 10 antibody
    • Bcl2 L 10 antibody
    • BCL2 like 10 (apoptosis facilitator) antibody
    • BCL2 like 10 protein antibody
    • Bcl2-L-10 antibody
    • Bcl2l10 antibody
    • BCLB antibody
    • Boo antibody
    • Diva antibody
    • MGC129810 antibody
    • MGC129811 antibody
    • Nrh antibody
    see all

Images

  • All lanes : Anti-BCL2L10 antibody - Aminoterminal end (ab45412) at 1 µg/ml

    Lane 1 : Jurkat cell lysate
    Lane 2 : Jurkat cell lysate + blocking peptide


    Predicted band size : 23 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)

References

This product has been referenced in:
  • Beverly LJ  et al. Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1. Proc Natl Acad Sci U S A 109:E119-26 (2012). WB, ICC/IF ; Human . Read more (PubMed: 22233804) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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