• Product name
  • Description
    Rabbit polyclonal to Bcl6
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide:


    , corresponding to amino acids 525-540 of Human Bcl6.

  • Positive control
    • Ramos cell lysate.
  • General notes
    Stable for 6 months at 4 °C.



Our Abpromise guarantee covers the use of ab13869 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 78 kDa.


  • Function
    Transcriptional repressor which is required for germinal center formation and antibody affinity maturation. Probably plays an important role in lymphomagenesis.
  • Tissue specificity
    Expressed in germinal center T and B cells and in primary immature dendritic cells.
  • Involvement in disease
    Note=Chromosomal aberrations involving BCL6 may be a cause of B-cell non-Hodgkin lymphoma. Translocation t(3;14)(q27;q32); translocation t(3;22)(q27;q11) with immunoglobulin gene regions.
    Note=A chromosomal aberration involving BCL6 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with POU2AF1/OBF1.
    Note=A chromosomal aberration involving BCL6 may be a cause of lymphoma. Translocation t(3;4)(q27;p11) with ARHH/TTF.
  • Sequence similarities
    Contains 1 BTB (POZ) domain.
    Contains 6 C2H2-type zinc fingers.
  • Domain
    The BTB domain mediates homodimerization. Its dimer interface mediates peptide binding such as to corepressors BCOR and NCOR2.
  • Post-translational
    Phosphorylated by MAPK1 in response to antigen receptor activation. Phosphorylation induces its degradation by ubiquitin/proteasome pathway.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • B cell CLL/lymphoma 6 antibody
    • B cell lymphoma 6 protein antibody
    • B-cell lymphoma 5 protein antibody
    • B-cell lymphoma 6 protein antibody
    • BCL 5 antibody
    • Bcl 6 antibody
    • BCL-5 antibody
    • BCL-6 antibody
    • BCL5 antibody
    • BCL6 antibody
    • BCL6_HUMAN antibody
    • BCL6A antibody
    • cys his2 zinc finger transcription factor antibody
    • LAZ 3 antibody
    • LAZ 3 protein antibody
    • LAZ3 antibody
    • Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3) antibody
    • Lymphoma associated zinc finger gene on chromosome 3 antibody
    • Protein LAZ-3 antibody
    • ZBTB 27 antibody
    • ZBTB27 antibody
    • Zinc finger and BTB domain containing protein 27 antibody
    • Zinc finger and BTB domain-containing protein 27 (ZBTB27) antibody
    • Zinc finger and BTB domain-containing protein 27 antibody
    • Zinc Finger Protein 51 (ZNF51) antibody
    • Zinc finger protein 51 antibody
    • zinc finger transcription factor BCL6S antibody
    • ZNF 51 antibody
    • ZNF51 antibody
    see all


  • Predicted band size : 78 kDa

    Western blot analysis of Bcl6 in 20 µgs of Ramos cell lysate using antibody at 1 µg/ml.


ab13869 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Thank you for your email. The free of charge replacement vial is being sent to your attention on order reference # 110953 and you should receive it Wednesday. Please let me know how it works out for you and if you have any additional questions.

Thank you for your email and for re-sending the image. Unfortunately, without the molecular weight markers on the image, it's difficult to determine the band size. But based on what you previously said, it seems that in the lanes that contain the Ramos...

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Thank you for your enquiry and I'm sorry to hear that you are experiencing difficulty with ab13869. Can you please tell me how your lysate was prepared? Would you be able to send me an image (jpg file) of your blot? This will help to give me a better i...

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