Overview

  • Product name
    Anti-BCMA antibody [MM0108-3D44]
    See all BCMA primary antibodies
  • Description
    Rat monoclonal [MM0108-3D44] to BCMA
  • Tested applications
    Suitable for: WB, Inhibition Assaymore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment (Human) - extracellular domain

Properties

Applications

Our Abpromise guarantee covers the use of ab89152 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 20 kDa.
Inhibition Assay Use at an assay dependent dilution.

Target

  • Function
    Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
  • Tissue specificity
    Expressed in mature B-cells, but not in T-cells or monocytes.
  • Involvement in disease
    Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
  • Sequence similarities
    Contains 1 TNFR-Cys repeat.
  • Cellular localization
    Cell membrane. Endomembrane system. Perinuclear Golgi-like structures.
  • Information by UniProt
  • Database links
  • Alternative names
    • B cell maturation antigen antibody
    • B cell maturation factor antibody
    • B cell maturation protein antibody
    • B-cell maturation protein antibody
    • BCM antibody
    • BCMA antibody
    • CD269 antibody
    • CD269 antigen antibody
    • TNFRSF17 antibody
    • TNR17_HUMAN antibody
    • Tumor necrosis factor receptor superfamily member 17 antibody
    see all

References

ab89152 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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