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Rat monoclonal [MM0108-3D44] to BCMA
Recombinant fragment (Human) - extracellular domain
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Concentration information loading...
Protein G purified
The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and 0.2 µm filtered.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/500 - 1/1000. Predicted molecular weight: 20 kDa.
||Use at an assay dependent dilution.
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Expressed in mature B-cells, but not in T-cells or monocytes.
Involvement in disease
Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
Contains 1 TNFR-Cys repeat.
Cell membrane. Endomembrane system. Perinuclear Golgi-like structures.
Information by UniProt
- B cell maturation antigen antibody
- B cell maturation factor antibody
- B cell maturation protein antibody
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"