Overview

  • Product nameAnti-Beclin 1 antibody [4A10]
    See all Beclin 1 primary antibodies
  • Description
    Mouse monoclonal [4A10] to Beclin 1
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein of Human Beclin 1 (NP_003757) produced in HEK293T cells.

  • Positive control
    • WB: Beclin 1 transfected HEK293T cell lysate ICC/IF: COS7 cells transiently transfected with Beclin 1
  • General notesDilute in PBS (pH 7.3) before use.

Properties

Applications

Our Abpromise guarantee covers the use of ab118148 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 52 kDa.
ICC/IF 1/100.

Target

  • FunctionPlays a central role in autophagy (By similarity). May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesBelongs to the beclin family.
  • Cellular localizationGolgi apparatus > trans-Golgi network membrane. Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • APG6 antibody
    • ATG 6 antibody
    • ATG6 antibody
    • ATG6 autophagy related 6 homolog antibody
    • Bcl-2-interacting protein beclin antibody
    • Beclin 1 (coiled coil moesin like BCL2 interacting protein) antibody
    • Beclin 1 autophagy related antibody
    • Beclin-1 antibody
    • Beclin1 antibody
    • BECN 1 antibody
    • Becn1 antibody
    • BECN1_HUMAN antibody
    • Coiled coil myosin like BCL2 interacting protein antibody
    • Coiled-coil myosin-like BCL2-interacting protein antibody
    • GT197 antibody
    • Protein GT197 antibody
    • VPS 30 antibody
    • VPS30 antibody
    see all

Anti-Beclin 1 antibody [4A10] images

  • All lanes : Anti-Beclin 1 antibody [4A10] (ab118148) at 1/2000 dilution

    Lane 1 : HEK293T cells transfected with pCMV6-ENTRY control
    Lane 2 : HEK293T cells transfected with pCMV6-ENTRY Beclin 1

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 52 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC201629)
  • Immunofluorescent staining of COS7 cells transiently transfected with pCMV6-ENTRY Beclin 1, using ab118148 at a dilution of 1/100.

References for Anti-Beclin 1 antibody [4A10] (ab118148)

ab118148 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"