Overview

  • Product nameAnti-Beclin 1 antibody
    See all Beclin 1 primary antibodies
  • Description
    Rabbit polyclonal to Beclin 1
  • Tested applicationsSuitable for: WB, ELISA, IHC-P, ICCmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    A 16 amino acid KLH conjugated synthetic peptide from near the C-terminus of Human Beclin 1.

  • Positive control
    • A431 cells, Human Heart, Kidney and Lung (Respiratory Epithelium) tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab109631 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 52 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC Use a concentration of 1 µg/ml.

Target

  • FunctionPlays a central role in autophagy (By similarity). May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesBelongs to the beclin family.
  • Cellular localizationGolgi apparatus > trans-Golgi network membrane. Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • APG6 antibody
    • ATG 6 antibody
    • ATG6 antibody
    • ATG6 autophagy related 6 homolog antibody
    • Bcl-2-interacting protein beclin antibody
    • Beclin 1 (coiled coil moesin like BCL2 interacting protein) antibody
    • Beclin 1 autophagy related antibody
    • Beclin-1 antibody
    • Beclin1 antibody
    • BECN 1 antibody
    • Becn1 antibody
    • BECN1_HUMAN antibody
    • Coiled coil myosin like BCL2 interacting protein antibody
    • Coiled-coil myosin-like BCL2-interacting protein antibody
    • GT197 antibody
    • Protein GT197 antibody
    • VPS 30 antibody
    • VPS30 antibody
    see all

Anti-Beclin 1 antibody images

  • Lane 1 : Anti-Beclin 1 antibody (ab109631) at 0.5 µg/ml
    Lane 2 : Anti-Beclin 1 antibody (ab109631) at 1 µg/ml
    Lane 3 : Anti-Beclin 1 antibody (ab109631) at 2 µg/ml

    Lane 1 : A431 cell lysate
    Lane 2 : A431 cell lysate
    Lane 3 : A431 cell lysate


    Predicted band size : 52 kDa
  • Human Heart (formalin-fixed, paraffin-embedded) stained with ab109631 at a concentration of 2.5 ug/ml.
  • Human Kidney (formalin-fixed, paraffin-embedded) stained with ab109631 at a concentration of 2.5 ug/ml.
  • Human Lung, Respiratory Epithelium (formalin-fixed, paraffin-embedded) stained with ab109631 at a concentration of 2.5 ug/ml.
  • Immunocytochemistry staining of A431 cells using ab109631 at a concentration of 1 µg/ml.

References for Anti-Beclin 1 antibody (ab109631)

ab109631 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"