Overview

Description

  • Nature
    Synthetic

Specifications

Our Abpromise guarantee covers the use of ab39729 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: PBS, 0.1% bovine serum albumin, pH 7.2

General Info

  • Alternative names
    • APG6
    • ATG 6
    • ATG6
    • ATG6 autophagy related 6 homolog
    • Bcl-2-interacting protein beclin
    • Beclin 1 (coiled coil moesin like BCL2 interacting protein)
    • Beclin 1 autophagy related
    • Beclin-1
    • Beclin1
    • BECN 1
    • Becn1
    • BECN1_HUMAN
    • Coiled coil myosin like BCL2 interacting protein
    • Coiled-coil myosin-like BCL2-interacting protein
    • GT197
    • Protein GT197
    • VPS 30
    • VPS30
    see all
  • Function
    Plays a central role in autophagy (By similarity). May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the beclin family.
  • Cellular localization
    Golgi apparatus > trans-Golgi network membrane. Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells.
  • Information by UniProt

References

ab39729 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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