Anti-beta 1 Adrenergic Receptor antibody (ab64996)

Overview

  • Product nameAnti-beta 1 Adrenergic Receptor antibody
    See all beta 1 Adrenergic Receptor primary antibodies
  • Description
    Rabbit polyclonal to beta 1 Adrenergic Receptor
  • Tested applicationsELISA, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from internal sequence of human beta 1 Adrenergic Receptor.

  • Positive control
    • Extracts from HT-29 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab64996 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/20000.
WB 1/500 - 1/1000. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).

Target

  • FunctionBeta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB1 sub-subfamily.
  • DomainThe PDZ domain-binding motif mediates competitive interactions with GOPC, MAGI3 and DLG4 and plays a role in subcellular location of the receptor.
  • Post-translational
    modifications
    Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase.
  • Cellular localizationCell membrane. Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression.
  • Information by UniProt
  • Database links
  • Alternative names
    • ADR B1 antibody
    • ADRB 1 antibody
    • ADRB1 antibody
    • ADRB1_HUMAN antibody
    • ADRB1R antibody
    • Adrenergic beta 1 receptor antibody
    • Adrenoceptor beta 1 antibody
    • B1AR antibody
    • Beta 1 adrenoceptor antibody
    • Beta 1 adrenoreceptor antibody
    • Beta-1 adrenergic receptor antibody
    • Beta-1 adrenoceptor antibody
    • Beta-1 adrenoreceptor antibody
    • BETA1AR antibody
    • RHR antibody
    see all

Anti-beta 1 Adrenergic Receptor antibody images

  • All lanes : Anti-beta 1 Adrenergic Receptor antibody (ab64996) at 1/500 dilution

    Lane 1 : Extracts from HT-29 cells (5-30 µg of total protein)
    Lane 2 : Extracts from HT-29 cells (5-30 µg of total protein) with 5-10µg of the immunising peptide


    Predicted band size : 51 kDa
    Observed band size : 51 kDa

References for Anti-beta 1 Adrenergic Receptor antibody (ab64996)

ab64996 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab64996.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"