Anti-beta 1 Adrenergic Receptor antibody (ab103653)

Overview

  • Product nameAnti-beta 1 Adrenergic Receptor antibody
    See all beta 1 Adrenergic Receptor primary antibodies
  • Description
    Rabbit polyclonal to beta 1 Adrenergic Receptor
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Guinea pig, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acides 180-229 (CTVWAISALV SFLPILMHWW RAESDEARRC YNDPKCCDFV TNRAYAIASS) of Human beta 1 Adrenergic Receptor (NP_000675).

  • Positive control
    • Fetal Brain Lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab103653 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 51 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionBeta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB1 sub-subfamily.
  • DomainThe PDZ domain-binding motif mediates competitive interactions with GOPC, MAGI3 and DLG4 and plays a role in subcellular location of the receptor.
  • Post-translational
    modifications
    Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase.
  • Cellular localizationCell membrane. Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression.
  • Information by UniProt
  • Database links
  • Alternative names
    • ADR B1 antibody
    • ADRB 1 antibody
    • ADRB1 antibody
    • ADRB1_HUMAN antibody
    • ADRB1R antibody
    • Adrenergic beta 1 receptor antibody
    • Adrenoceptor beta 1 antibody
    • B1AR antibody
    • Beta 1 adrenoceptor antibody
    • Beta 1 adrenoreceptor antibody
    • Beta-1 adrenergic receptor antibody
    • Beta-1 adrenoceptor antibody
    • Beta-1 adrenoreceptor antibody
    • BETA1AR antibody
    • RHR antibody
    see all

Anti-beta 1 Adrenergic Receptor antibody images



  • Predicted band size : 51 kDa
    Western blot analysis of Human fetal muscle tissue lysate labeling beta 1 Adrenergic Receptor with ab103653 at 1.0µg/ml.


  • Predicted band size : 51 kDa
    Western blot analysis of Human fetal lung tissue lysate labeling beta 1 Adrenergic Receptor with ab103653 at 1.0µg/ml.


  • Predicted band size : 51 kDa
    Western blot analysis of Human fetal liver tissue lysate labeling beta 1 Adrenergic Receptor with ab103653 at 1.0µg/ml.


  • Predicted band size : 51 kDa
    Western blot analysis of Human fetal heart tissue lysate labeling beta 1 Adrenergic Receptor with ab103653 at 1.0µg/ml.


  • Predicted band size : 51 kDa
    Western blot analysis of Human adult placenta tissue lysate labeling beta 1 Adrenergic Receptor with ab103653 at 1.0µg/ml.
  • Anti-beta 1 Adrenergic Receptor antibody (ab103653) at 1 µg/ml + Fetal Brain Lysate at 10 µg

    Predicted band size : 51 kDa
    Gel concentration: 12%

References for Anti-beta 1 Adrenergic Receptor antibody (ab103653)

ab103653 has not yet been referenced specifically in any publications.

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Thank you for providing all this information. You have clearly performed a set of carefully though out experiments and the ab103653 antibody does not appear to be producing the results expected. I thought the human IgG present in the samples may have b...

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