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Product Name
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beta 2 Defensin antibody
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See all beta 2 Defensin antibodies (6)...
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Product type
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Primary antibodies
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Description
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Goat polyclonal to beta 2 Defensin
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Immunogen
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Highly pure (>98%) recombinant hBD-2 (human Beta Defensin-2)
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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ELISA, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions ELISA:To detect hBD-2 by direct ELISA (using 100µl/well antibody solution) a concentration of at least 0.5µg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant hBD-2.
Western Blot:To detect hBD-2 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hBD-2 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions
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Positive control
(see definition)
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recombinant hBD-2 (human Beta Defensin-2) ab9872
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Cellular localization
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Secreted
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Research areas
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Immunology >> Secreted Molecules >> Other secreted molecules Microbiology >> Protein >> Human Protein >> Defensin
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Relevance
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This antibiotic peptide is locally regulated by inflammation. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence.
hBD-2 is a antimicrobial peptide, which belongs to the distinct family of beta-defensins.
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Database links
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The links below go to external sites and will open in a new browser window
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Raised in
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Goat
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Clonality
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Polyclonal
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Purity
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Immunogen affinity purified
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Storage buffer
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Phosphate buffered saline
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this beta 2 Defensin antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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References for beta 2 Defensin antibody (ab9871)
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This product has been used in: (two most recent references)
Pignatti P et al. Tracheostomy and related host-pathogen interaction are associated with airway inflammation as characterized by tracheal aspirate analysis. Respir Med 103:201-8 (2009). PubMed: 18980836
Herr C et al. Suppression of pulmonary innate host defence in smokers. Thorax 64:144-9 (2009). PubMed: 18852155
See all 3 publication references for this product.
If you publish research using ab9871 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to beta 2 Defensin
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