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Product Name 

beta 2 Defensin antibody

 

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Product type 

Primary antibodies

Description 

Goat polyclonal to beta 2 Defensin

Immunogen 

Highly pure (>98%) recombinant hBD-2 (human Beta Defensin-2)

Reacts with 
(species key)

Hu

Tested applications 
(see key)

ELISA, WB


Abreviews 

Customer reviews
(see key)


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• ELISA

1 Abreview

 


Application notes 
(see key)

Recommended dilutions
ELISA:To detect hBD-2 by direct ELISA (using 100µl/well antibody solution) a concentration of at least 0.5µg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant hBD-2.

Western Blot:To detect hBD-2 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hBD-2 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions

Positive control 
(see definition)

recombinant hBD-2 (human Beta Defensin-2) ab9872

Cellular localization 

Secreted

Research areas 

Immunology >> Secreted Molecules >> Other secreted molecules
Microbiology >> Protein >> Human Protein >> Defensin

Relevance 

This antibiotic peptide is locally regulated by inflammation. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence.

hBD-2 is a antimicrobial peptide, which belongs to the distinct family of beta-defensins.

 

Alternative names beta 2 Defensin antibody (ab9871)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

1673    (Human)

Omim

    

602215    (Human)

SwissProt

    

O15263    (Human)

Unigene

    

105924    (Human)

Raised in 

Goat

Clonality 

Polyclonal

Purity 

Immunogen affinity purified

Storage buffer 

Phosphate buffered saline

Form 

Liquid

Concentration 

0.500 mg/ml

Storage instructions 

Store at +4°C.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this beta 2 Defensin antibody is on this datasheet. But please do contact us if you would like any reassurance!



References for beta 2 Defensin antibody (ab9871)

Specific publication references   This product has been used in: (two most recent references)

Pignatti P et al. Tracheostomy and related host-pathogen interaction are associated with airway inflammation as characterized by tracheal aspirate analysis. Respir Med 103:201-8 (2009). PubMed: 18980836

Herr C et al. Suppression of pulmonary innate host defence in smokers. Thorax 64:144-9 (2009). PubMed: 18852155


See all 3 publication references for this product.


If you publish research using ab9871 please let us know so that we can cite the reference on this datasheet.

 

Search PubMed (MEDLINE) for references to beta 2 Defensin

 

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beta 2 Defensin antibody - related products:

Products for Western blot

Loading controls

Lysates

 

Positive Controls for beta 2 Defensin antibody

ab9872

  

beta 2 Defensin protein

 

Compatible Secondaries for beta 2 Defensin antibody

ab6566

  

Cy5 ® antibody

ab6739

  

Texas Red ® antibody

ab6740

  

Biotin antibody

ab6741

  

HRP antibody

ab6742

  

Alkaline Phosphatase antibody

ab6881

  

FITC antibody

ab7004

  

Phycoerythrin antibody

ab27245

  

10nm Gold antibody

ab27246

  

10nm Gold antibody

ab27247

  

15nm Gold antibody

 

Other beta 2 Defensin Antibodies

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