Overview

  • Product name
    Anti-beta 3 Adrenergic Receptor antibody
    See all beta 3 Adrenergic Receptor primary antibodies
  • Description
    Goat polyclonal to beta 3 Adrenergic Receptor
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee
  • Immunogen

    Synthetic peptide:

    PHENSSLAPWPD-C

    , corresponding to N terminal amino acids 5-16 of human beta 3 Adrenergic Receptor (NP_000016.1)

  • Positive control
    • Human brain (cerebellum, cerebral cortex, frontal cortex) lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab77588 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    Peptide ELISA: Antibody detection limit dilution 1/128000.
    WB: Use at a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
    • Tissue specificity
      Expressed mainly in adipose tissues.
    • Sequence similarities
      Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • ADR B3 antibody
      • ADRB 3 antibody
      • ADRB3 antibody
      • ADRB3_HUMAN antibody
      • ADRB3R antibody
      • Adrenergic beta 3 receptor antibody
      • B3AR antibody
      • Beta 3 adrenoceptor antibody
      • Beta 3 adrenoreceptor antibody
      • Beta 3AR antibody
      • Beta-3 adrenergic receptor antibody
      • Beta-3 adrenoceptor antibody
      • Beta-3 adrenoreceptor antibody
      • Beta3AR antibody
      • FLJ99960 antibody
      see all

    Images

    • Anti-beta 3 Adrenergic Receptor antibody (ab77588) at 0.03 µg/ml + human brain (cerebral cortex) lysate (in RIPA buffer) at 35 µg

      Predicted band size : 45 kDa
      Observed band size : 45 kDa

    References

    This product has been referenced in:
    • O'Leary AP  et al. Beta-Adrenoceptor Activation Reduces Both Dermal Microvascular Endothelial Cell Migration Via a cAMP-Dependent Mechanism and Wound Angiogenesis. J Cell Physiol N/A:N/A (2014). WB ; Human . Read more (PubMed: 24986762) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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