Validated using a knockout cell line

Anti-beta Catenin antibody [E247] (ab32572)

Publishing research using ab32572? Please let us know so that we can cite the reference in this datasheet.

ab32572 has been referenced in 66 publications.

  • Huang H  et al. Tissue transglutaminase-1 promotes stemness and chemoresistance in gastric cancer cells by regulating Wnt/ß-catenin signaling. Exp Biol Med (Maywood) 242:194-202 (2017). PubMed: 27660242
  • Lu T  et al. Adamts18 deficiency promotes colon carcinogenesis by enhancing ß-catenin and p38MAPK/ERK1/2 signaling in the mouse model of AOM/DSS-induced colitis-associated colorectal cancer. Oncotarget 8:18979-18990 (2017). IHC ; Mouse . PubMed: 28145888
  • Yuan J  et al. M2 microglia promotes neurogenesis and oligodendrogenesis from neural stem/progenitor cells via the PPAR? signaling pathway. Oncotarget 8:19855-19865 (2017). WB ; Mouse . PubMed: 28423639
  • Sun L  et al. Oct4 induces EMT through LEF1/ß-catenin dependent WNT signaling pathway in hepatocellular carcinoma. Oncol Lett 13:2599-2606 (2017). ICC/IF ; Human . PubMed: 28454439
  • Zhang H  et al. Pigment epithelium-derived factor attenuates myocardial fibrosis via inhibiting Endothelial-to-Mesenchymal Transition in rats with acute myocardial infarction. Sci Rep 7:41932 (2017). ICC/IF ; Rat . PubMed: 28167820
  • Das L  et al. Membrane-bound ß-catenin degradation is enhanced by ETS2-mediated Siah1 induction in Helicobacter pylori-infected gastric cancer cells. Oncogenesis 6:e327 (2017). WB, FM ; Human . PubMed: 28481365
  • Zhang HT  et al. Andrographolide Induces Cell Cycle Arrest and Apoptosis of Chondrosarcoma by Targeting TCF-1/SOX9 Axis. J Cell Biochem N/A:N/A (2017). Mouse . PubMed: 28485543
  • Wang T  et al. Fibulin-4 is associated with prognosis of endometrial cancer patients and inhibits cancer cell invasion and metastasis via Wnt/ß-catenin signaling pathway. Oncotarget 8:18991-19012 (2017). WB ; Human . PubMed: 28177909
  • Cheng G  et al. Lipopolysaccharide-induced a-catenin downregulation enhances the motility of human colorectal cancer cells in an NF-?B signaling-dependent manner. Onco Targets Ther 9:7563-7571 (2016). PubMed: 28008274
  • Zhang X  et al. MicroRNA-195 suppresses colorectal cancer cells proliferation via targeting FGF2 and regulating Wnt/ß-catenin pathway. Am J Cancer Res 6:2631-2640 (2016). WB ; Human . PubMed: 27904776
  • Duan ZZ  et al. Protease activated receptor 1 (PAR1) enhances Src-mediated tyrosine phosphorylation of NMDA receptor in intracerebral hemorrhage (ICH). Sci Rep 6:29246 (2016). PubMed: 27385592
  • Li P  et al. The expression of presenilin 1 enhances carcinogenesis and metastasis in gastric cancer. Oncotarget 7:10650-62 (2016). WB ; Human . PubMed: 26872378
  • Wu L  et al. Sclerostin expression in the subchondral bone of patients with knee osteoarthritis. Int J Mol Med 38:1395-1402 (2016). WB, IHC-P ; Human . PubMed: 27665782
  • Wu Y  et al. Low expression of secreted frizzled-related protein 2 and nuclear accumulation of ß-catenin in aggressive nonfunctioning pituitary adenoma. Oncol Lett 12:199-206 (2016). WB, IHC-P ; Human . PubMed: 27347125
  • Qu F  et al. MicroRNA-26a induces osteosarcoma cell growth and metastasis via the Wnt/ß-catenin pathway. Oncol Lett 11:1592-1596 (2016). WB ; Human . PubMed: 26893786
  • Liang H  et al. MSX2 Induces Trophoblast Invasion in Human Placenta. PLoS One 11:e0153656 (2016). WB . PubMed: 27088357
  • Montalbano M  et al. Modeling of Hepatocytes Proliferation Isolated from Proximal and Distal Zones from Human Hepatocellular Carcinoma Lesion. PLoS One 11:e0153613 (2016). WB, IHC-P ; Human . PubMed: 27074018
  • Nietzer S  et al. Mimicking Metastases Including Tumor Stroma: A New Technique to Generate a Three-Dimensional Colorectal Cancer Model Based on a Biological Decellularized Intestinal Scaffold. Tissue Eng Part C Methods 22:621-35 (2016). IHC-P ; Human . PubMed: 27137941
  • Tura A  et al. Biocompatibility of the vital dye Acid Violet-17 on retinal pigment epithelial cells. Clin Ophthalmol 10:1435-45 (2016). PubMed: 27536056
  • Rossi SP  et al. Reactive oxygen species (ROS) production triggered by prostaglandin D2 (PGD2) regulates lactate dehydrogenase (LDH) expression/activity in TM4 Sertoli cells. Mol Cell Endocrinol 434:154-65 (2016). PubMed: 27329155
  • Huang YW  et al. Black raspberries demethylate Sfrp4, a WNT pathway antagonist, in rat esophageal squamous cell papilloma. Mol Carcinog 55:1867-1875 (2016). PubMed: 27696538
  • Wang G  et al. Misexpression of BRE gene in the developing chick neural tube affects neurulation and somitogenesis. Mol Biol Cell 26:978-92 (2015). PubMed: 25568339
  • Chen J  et al. Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells. Mar Drugs 13:6259-73 (2015). PubMed: 26445050
  • Nguyen TT  et al. Generation and characterization of soluble interleukin-33 receptor fused with immunoglobulin gamma-1 constant domain expressed by Pichia pastoris yeast. J Pharm Pharmacol 67:329-37 (2015). PubMed: 25644762
  • Maywald RL  et al. IL-33 activates tumor stroma to promote intestinal polyposis. Proc Natl Acad Sci U S A 112:E2487-96 (2015). PubMed: 25918379
  • Wei YB  et al. Telomerase dysregulation in the hippocampus of a rat model of depression: normalization by lithium. Int J Neuropsychopharmacol 18:pyv002 (2015). WB ; Rat . PubMed: 25618407
  • Li Y  et al. Minocycline protects against hepatic ischemia/reperfusion injury in a rat model. Biomed Rep 3:19-24 (2015). WB ; Rat . PubMed: 25469240
  • Shi J  et al. Regulation of ß-catenin transcription activity by leupaxin in hepatocellular carcinoma. Tumour Biol N/A:N/A (2015). PubMed: 26361959
  • Jin X  et al. The Overexpression of IQGAP1 and ß-Catenin Is Associated with Tumor Progression in Hepatocellular Carcinoma In Vitro and In Vivo. PLoS One 10:e0133770 (2015). IHC ; Human . PubMed: 26252773
  • Cao C  et al. The long intergenic noncoding RNA UFC1, a target of MicroRNA 34a, interacts with the mRNA stabilizing protein HuR to increase levels of ß-catenin in HCC cells. Gastroenterology 148:415-26.e18 (2015). WB, IF . PubMed: 25449213
  • Tan BL  et al. Water extract of brewers' rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/ß-catenin downstream signaling pathway in brewers' rice-treated rats with azoxymethane-induced colon carcinogenesis. BMC Complement Altern Med 15:205 (2015). WB ; Rat . PubMed: 26122204
  • Zou Y  et al. Resveratrol inhibits canonical Wnt signaling in human MG-63 osteosarcoma cells. Mol Med Rep 12:7221-6 (2015). WB ; Human . PubMed: 26398440
  • Du C  et al. MiR-126-3p suppresses tumor metastasis and angiogenesis of hepatocellular carcinoma by targeting LRP6 and PIK3R2. J Transl Med 12:259 (2014). WB . PubMed: 25240815
  • Zhang J  et al. SOX4 inhibits GBM cell growth and induces G0/G1 cell cycle arrest through Akt-p53 axis. BMC Neurol 14:207 (2014). WB ; Human . PubMed: 25366337
  • Stratmann AT  et al. Establishment of a human 3D lung cancer model based on a biological tissue matrix combined with a Boolean in silico model. Mol Oncol 8:351-65 (2014). Human . PubMed: 24388494
  • Gieseck RL  et al. Maturation of induced pluripotent stem cell derived hepatocytes by 3D-culture. PLoS One 9:e86372 (2014). ICC/IF ; Human . PubMed: 24466060
  • Yang J  et al. Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines. Hum Mol Genet N/A:N/A (2014). WB . PubMed: 24497574
  • Yu DH  et al. The essential role of TNIK gene amplification in gastric cancer growth. Oncogenesis 2:e89 (2014). IHC ; Human . PubMed: 24566388
  • Luaces JP  et al. Loss of Sertoli-germ cell adhesion determines the rapid germ cell elimination during the seasonal regression of the seminiferous epithelium of the large hairy armadillo Chaetophractus villosus. Biol Reprod 90:48 (2014). PubMed: 24451984
  • Ng OH  et al. Deregulated WNT signaling in childhood T-cell acute lymphoblastic leukemia. Blood Cancer J 4:e192 (2014). WB ; Human . PubMed: 24632884
  • Ma M  et al. Wnt signaling in form deprivation myopia of the mice retina. PLoS One 9:e91086 (2014). WB ; Mouse . PubMed: 24755605
  • Liu N  et al. Wnt/ß-Catenin Pathway Regulates Cementogenic Differentiation of Adipose Tissue-Deprived Stem Cells in Dental Follicle Cell-Conditioned Medium. PLoS One 9:e93364 (2014). WB, ICC/IF ; Rat . PubMed: 24806734
  • Benamrouz S  et al. Cryptosporidium parvum-induced ileo-caecal adenocarcinoma and Wnt signaling in a mouse model. Dis Model Mech 7:693-700 (2014). ICC/IF ; Mouse . PubMed: 24652769
  • Gao B  et al. Dose-Dependent Effect of Estrogen Suppresses the Osteo-Adipogenic Transdifferentiation of Osteoblasts via Canonical Wnt Signaling Pathway. PLoS One 9:e99137 (2014). Mouse . PubMed: 24918446
  • Ndisang JF & Tiwari S Induction of heme oxygenase with hemin improves pericardial adipocyte morphology and function in obese Zucker rats by enhancing proteins of regeneration. Exp Biol Med (Maywood) N/A:N/A (2014). Rat . PubMed: 25053781
  • Okuda Y  et al. Wnt signaling as a possible promoting factor of cell differentiation in pleomorphic adenomas. Int J Med Sci 11:971-8 (2014). IHC-P ; Human . PubMed: 25076852
  • Shen YL  et al. Bone marrow mesenchymal stem cell-derived Wnt5a inhibits leukemia cell progression in vitro via activation of the non-canonical Wnt signaling pathway. Oncol Lett 8:85-90 (2014). WB . PubMed: 24959224
  • Roscilli G  et al. Carnitines slow down tumor development of colon cancer in the DMH-chemical carcinogenesis mouse model. J Cell Biochem 114:1665-73 (2013). Mouse . PubMed: 23386399
  • Chu IM  et al. Expression of GATA3 in MDA-MB-231 triple-negative breast cancer cells induces a growth inhibitory response to TGFß. PLoS One 8:e61125 (2013). WB ; Human . PubMed: 23577196
  • Wang WY  et al. A Gene Expression Signature of Epithelial Tubulogenesis and a Role for ASPM in Pancreatic Tumor Progression. Gastroenterology 145:1110-20 (2013). IHC-P ; Human . PubMed: 23896173
  • Monteiro J  et al. Cancer stemness in Wnt-driven mammary tumorigenesis. Carcinogenesis N/A:N/A (2013). IHC-P ; Mouse . PubMed: 23955540
  • Jiang Q  et al. Gamma-tocopherol attenuates moderate but not severe colitis and suppresses moderate colitis-promoted colon tumorigenesis in mice. Free Radic Biol Med 65C:1069-1077 (2013). PubMed: 24013093
  • Lu W  et al. Spatiotemporal expression of Wnt signaling pathway components during bovine placental development. Theriogenology 80:893-902 (2013). IHC-P, ICC/IF ; Cow . PubMed: 24007824
  • Tan X  et al. Loss of p53 attenuates the contribution of IL-6 deletion on suppressed tumor progression and extended survival in Kras-driven murine lung cancer. PLoS One 8:e80885 (2013). WB ; Mouse . PubMed: 24260500
  • Zhao L  et al. JMJD2B promotes epithelial-mesenchymal transition by cooperating with ß-catenin and enhances gastric cancer metastasis. Clin Cancer Res 19:6419-29 (2013). PubMed: 24077348
  • Yao W  et al. Knockdown of ß-catenin expression inhibits neuroblastoma cell growth in vitro and in vivo. J Pediatr Surg 48:2466-73 (2013). Mouse . PubMed: 24314188
  • Hoenerhoff MJ  et al. Hepatocellular Carcinomas in B6C3F1 Mice Treated with Ginkgo biloba Extract for Two Years Differ from Spontaneous Liver Tumors in Cancer Gene Mutations and Genomic Pathways. Toxicol Pathol : (2012). PubMed: 23262642
  • Lade A  et al. Calpain induces N-terminal truncation of ß-catenin in normal murine liver development: Diagnostic implications in hepatoblastomas. J Biol Chem : (2012). WB, IHC-P . PubMed: 22613727
  • Xiang T  et al. The ubiquitin peptidase UCHL1 induces G0/G1 cell cycle arrest and apoptosis through stabilizing p53 and is frequently silenced in breast cancer. PLoS One 7:e29783 (2012). WB . PubMed: 22279545
  • Vuoriluoto K  et al. Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer. Oncogene 30:1436-48 (2011). PubMed: 21057535
  • Jones WM  et al. Cytokinesis proteins Tum and Pav have a nuclear role in Wnt regulation. J Cell Sci 123:2179-89 (2010). WB, ICC/IF ; Human . PubMed: 20516152
  • Norwood MG  et al. Cytoplasmic beta-catenin accumulation is a good prognostic marker in upper and lower gastrointestinal adenocarcinomas. Histopathology 57:101-11 (2010). IHC-P ; Human . PubMed: 20572881
  • Xue Y  et al. Generation of a transgenic mouse for colorectal cancer research with intestinal cre expression limited to the large intestine. Mol Cancer Res 8:1095-104 (2010). IHC-P ; Mouse . PubMed: 20663863
  • Kneidinger N  et al. Activation of the WNT/{beta}-Catenin Pathway Attenuates Experimental Emphysema. Am J Respir Crit Care Med : (2010). PubMed: 20889911
  • Galli C  et al. Rough surface topography enhances the activation of Wnt/ß-catenin signaling in mesenchymal cells. J Biomed Mater Res A 95:682-90 (2010). ICC/IF ; Mouse . PubMed: 20725985
  • Lock FE  et al. The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-kappaB signaling pathways. Oncogene 29:4307-16 (2010). WB, ICC/IF ; Human . PubMed: 20514026


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