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Products:Immunology >> Innate Immunity >> Macrophage / Inflamm.
Overview
Product name
Anti-beta Defensin 3 antibody
See all beta Defensin 3 products (5) ...
Description
Rabbit polyclonal to beta Defensin 3
Specificity
This antibody reacts with the 5 kDa hBD-3 protein.
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide: GIINTLQKYYC, corresponding to amino acids 23/33 of Human beta 3 Defensin
GIINTLQKYY C
Epitope
This antibody reacts with residues 23-33 [GIINTLQKYYC]of the 5 kDa hBD-3 protein.The numbering referred to the precursor of the protein (1-11 of the mature functional peptide).
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
PBS with 0.02% sodium azide
Concentration
Concentration information loading...
Purity
IgG fraction
Clonality
Polyclonal
Isotype
IgG
Light chain type
unknown
Research areas
Microbiology >> Protein >> Human Protein >> Defensin
Immunology >> Innate Immunity >> Macrophage / Inflamm.
Applications
Show applications key
Our Abpromise guarantee covers the use of ab1128 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
WB: 1/500((ECL).)WB: 1/500((ECL).)
Target
Function
Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed.
Tissue specificity
Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine.
Sequence similarities
Belongs to the beta-defensin family.
Cellular localization
Secreted.
Target information above from: UniProt accessionP81534
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- beta 103 antibody
- BD 3 antibody
- BD-3 antibody
see all
Database links
- Entrez Gene: 414325 Human
- Entrez Gene: 55894 Human
- Omim: 606611 Human
- SwissProt: P81534 Human
- Unigene: 283082 Human
- Unigene: 637221 Human
References for Anti-beta Defensin 3 antibody (ab1128)
ab1128 has not yet been referenced specifically in any publications.
Publishing research using ab1128? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"