Recombinant
RabMAb

Anti-beta Crystallin A3 antibody [EPR9585] (ab151713)

Overview

  • Product name
    Anti-beta Crystallin A3 antibody [EPR9585]
    See all beta Crystallin A3 primary antibodies
  • Description
    Rabbit monoclonal [EPR9585] to beta Crystallin A3
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, corresponding to residues in Human beta Crystallin A3 (UniProt: P05813).

  • Positive control
    • Mouse and Rat eyeball lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20ºC.
  • Storage buffer
    Preservative: 0.01% Sodium azide
    Constituents: 50% Glycerol, 0.05% BSA
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR9585
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab151713 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 25 kDa.
  • Application notes
    Is unsuitable for ICC/IF,IHC-P or IP.
  • Target

    • Function
      Crystallins are the dominant structural components of the vertebrate eye lens.
    • Involvement in disease
      Defects in CRYBA1 are the cause of cataract congenital zonular with sutural opacities (CCZS) [MIM:600881]. A form of zonular cataract. Zonular or lamellar cataracts are concentric opacities, broad or narrow, usually consisting of powdery white dots affecting one lamella or zonule of an otherwise clear lens.
    • Sequence similarities
      Belongs to the beta/gamma-crystallin family.
      Contains 4 beta/gamma crystallin 'Greek key' domains.
    • Domain
      Has a two-domain beta-structure, folded into four very similar Greek key motifs.
    • Post-translational
      modifications
      Specific cleavages in the N-terminal arm occur during lens maturation and give rise to several truncated forms. Cleavages do not seem to have adverse effects on solubility.
      S-methylation and glutathionylation occur in normal young lenses and do not seem to be detrimental.
      Isoform A1 initiator methionine is removed. The new N-terminal amino acid is then N-acetylated.
    • Information by UniProt
    • Database links
    • Alternative names
      • Beta crystallin A3 isoform A1 Delta4 form antibody
      • Beta crystallin A3 antibody
      • Beta crystallin A3 isoform A1 Delta7 form antibody
      • Beta crystallin A3 isoform A1 Delta8 form antibody
      • Beta-crystallin A3 antibody
      • CRBA1_HUMAN antibody
      • CRYB1 antibody
      • CRYBA1 antibody
      • Crystallin beta A1 antibody
      • Crystallin beta A3 antibody
      • Delta8 form antibody
      • Eye lens structural protein antibody
      • isoform A1 antibody
      see all

    Images

    • All lanes : Anti-beta Crystallin A3 antibody [EPR9585] (ab151713) at 1/1000 dilution

      Lane 1 : Mouse eyeball lysate
      Lane 2 : Rat eyeball lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size: 25 kDa

    References

    ab151713 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab151713.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up