Overview

  • Product name
    Anti-beta Sarcoglycan antibody
    See all beta Sarcoglycan primary antibodies
  • Description
    Rabbit polyclonal to beta Sarcoglycan
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide within Human beta Sarcoglycan aa 170-220 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    SITSDIGMQFFDPRTQNILFSTDYETHEFHLPSGVKSLNVQKASTERITS NATSDLNIKV


    Database link: Q16585

  • Positive control
    • Mouse stomach and rat pancreas tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab203392 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

Target

  • Function
    Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
  • Tissue specificity
    Highest expression in heart and skeletal muscle. Low expression in brain, kidney, placenta, pancreas and lung. High expression in fetal brain. Also found in fetal lung, kidney and liver.
  • Involvement in disease
    Limb-girdle muscular dystrophy 2E
  • Sequence similarities
    Belongs to the sarcoglycan beta/delta/gamma/zeta family.
  • Post-translational
    modifications
    Disulfide bonds are present.
  • Cellular localization
    Cell membrane, sarcolemma. Cytoplasm, cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • 43 kDa dystrophin associated glycoprotein antibody
    • 43 kDa dystrophin-associated glycoprotein antibody
    • 43DAG antibody
    • A3b antibody
    • Beta SG antibody
    • Beta-sarcoglycan antibody
    • Beta-SG antibody
    • dystrophin-associated glycoprotein, 43-kD antibody
    • LGMD2E antibody
    • Limb girdle muscular dystrophy 2E (non linked families) antibody
    • Sarcoglycan beta antibody
    • sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) antibody
    • SGC antibody
    • SGCB antibody
    • SGCB_HUMAN antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin embedded rat pancreas tissue labeling beta Sarcoglycan with ab203392 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

  • Immunohistochemical analysis of formalin-fixed, paraffin embedded mouse stomach tissue labeling beta Sarcoglycan with ab203392 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

References

ab203392 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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