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Products:Microbiology >> Toxin >> Bacterial Toxin >> Cholera Toxin
Overview
Product name
Anti-beta subunit Cholera Toxin antibody
See all beta subunit Cholera Toxin products (9) ...
Description
Chicken polyclonal to beta subunit Cholera Toxin
Tested applications
Cross reactivity
Bacterial toxin
Immunogen
Full length protein.
Positive control
CTXB protein as test antigen for WB.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein L purified
Clonality
Polyclonal
Isotype
IgY
Research areas
Microbiology >> Toxin >> Bacterial Toxin >> Cholera Toxin
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Western blot - Anti-beta subunit Cholera Toxin antibody (ab19106)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab19106 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/1000 - 1/2000.Detects a band of approximately 11 kDa.
Target
Relevance
The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.
Cellular localization
Secreted
Alternative names
- Cholera enterotoxin B chain antibody
- Cholera enterotoxin beta chain antibody
- Cholera enterotoxin gamma chain antibody
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Anti-beta subunit Cholera Toxin antibody images:
Western blot - Anti-beta subunit Cholera Toxin antibody (ab19106)
Ab19106 at a dilution of 1/2000, staining the beta subunit of Cholera toxin by Western blot. The arrow points to the CTXB protein.
References for Anti-beta subunit Cholera Toxin antibody (ab19106)
ab19106 has not yet been referenced specifically in any publications.
Publishing research using ab19106? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"