Overview

  • Product nameAnti-beta Synuclein antibody
    See all beta Synuclein primary antibodies
  • Description
    Chicken polyclonal to beta Synuclein
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Fusion protein, corresponding to amino acids 1-134 of Human beta Synuclein.

  • Positive control
    • E.Coli derived fusion protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab16420 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 15 kDa.

Target

  • FunctionNon-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
  • Tissue specificityExpressed predominantly in brain; concentrated in presynaptic nerve terminals.
  • Sequence similaritiesBelongs to the synuclein family.
  • Post-translational
    modifications
    Phosphorylated. Phosphorylation by G-protein coupled receptor kinases (GRK) is more efficient than phosphorylation by CK1, CK2 and CaM-kinase II.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • 14 kDa brain-specific protein antibody
    • Beta-synuclein antibody
    • Phosphoneuroprotein 14 antibody
    • PNP14 antibody
    • Sncb antibody
    • Synuclein beta antibody
    • SYUB_HUMAN antibody
    see all

Anti-beta Synuclein antibody images



  • Predicted band size : 15 kDa


    Ab16420 at a 1/2000 dilution staining beta Synuclein by Western blot. Colorimetric method was used for signal development. The arrow points to beta Synuclein fusion protein.

References for Anti-beta Synuclein antibody (ab16420)

ab16420 has not yet been referenced specifically in any publications.

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