Anti-BHLHA15 antibody [1H1/E5/E5] (ab111924)

Overview

  • Product nameAnti-BHLHA15 antibody [1H1/E5/E5]
    See all BHLHA15 primary antibodies
  • Description
    Mouse monoclonal [1H1/E5/E5] to BHLHA15
  • Specificityab111924 may also recognise LMTK2 lemur tyrosine kinase 2 gene ID 22853
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Human, Chimpanzee
  • Immunogen

    Synthetic peptide:

    MKTKNRPPRRRTPMQDTEAT

    , corresponding to N terminal amino acids 1-20 of Mouse BHLHA15 (Q9QYC3)

Properties

Applications

Our Abpromise guarantee covers the use of ab111924 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/250. Detects a band of approximately 29 kDa (predicted molecular weight: 21 kDa).

Target

  • FunctionPlays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.
  • Tissue specificityExpressed in brain, liver, spleen and skeletal muscle.
  • Sequence similaritiesContains 1 basic helix-loop-helix (bHLH) domain.
  • DomainLacks a classic transcription activation domain and instead possesses an N-terminal region capable of inhibiting heterologous activators.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Basic helix loop helix domain containing class B 8 antibody
    • Basic helix loop helix family member a15 antibody
    • BHA15_HUMAN antibody
    • Bhlha15 antibody
    • bHLHB8 antibody
    • Class A basic helix-loop-helix protein 15 antibody
    • Class B basic helix-loop-helix protein 8 antibody
    • Class II bHLH protein MIST1 antibody
    • intestine and stomach expression 1 antibody
    • MIST 1 antibody
    • MIST-1 antibody
    • MIST1 antibody
    • Muscle antibody
    • Muscle intestine and stomach expression 1 antibody
    • protein MIST1 antibody
    see all

References for Anti-BHLHA15 antibody [1H1/E5/E5] (ab111924)

ab111924 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab111924.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"