1/100 - 1/500. Antigen retrieval is not essential but may optimise staining.
FunctionInvolved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline.
Tissue specificityFound exclusively in liver and kidney.
PathwayAmine and polyamine degradation; betaine degradation; sarcosine from betaine: step 1/2. Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (BhmT route): step 1/1.
Immunohistochemical analysis of paraffin-embedded SG xenograft, using ab96415 at 1:100 dilution.
References for Anti-BHMT antibody (ab96415)
This product has been referenced in:
Zhang Y et al. Homocysteine homeostasis and betaine-homocysteine S-methyltransferase expression in the brain of hibernating bats. PLoS One8:e85632 (2013).
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