Overview

  • Product nameAnti-BICD2 antibody
    See all BICD2 primary antibodies
  • Description
    Rabbit polyclonal to BICD2
  • Tested applicationsSuitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Guinea pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • Immunogen

    Synthetic peptide, corresponding to a region between amino acids 625-675 of Human BICD2 (NP_056065.1).

  • Positive control
    • HeLa whole cell lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium azide
    Constituent: 99% Tris buffered saline
    Note: pH 7-8
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab117799 was affinity purified using an epitope specific to BICD2 immobilized on solid support.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab117799 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
  • Application notesIs unsuitable for WB.
  • Target

    • FunctionMay play a role in the dynein-dynactin interactions on the surface of membranous organelles, by associating with these complexes. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex.
    • Tissue specificityUbiquitous.
    • Sequence similaritiesBelongs to the BicD family.
    • DomainThe fourth coiled coil region is involved in Golgi targeting and in the interaction with DCTN2.
    • Post-translational
      modifications
      Phosphorylated by NEK9 in vitro.
    • Cellular localizationGolgi apparatus. Cytoplasm > cytoskeleton. In interphase cells mainly localizes to the Golgi complex and colocalizes with dynactin at microtubule plus ends (By similarity). Its localization is dependent on microtubule morphology.
    • Information by UniProt
    • Database links
    • Alternative names
      • bA526D8.1 antibody
      • Bic D 2 antibody
      • Bic-D 2 antibody
      • Bicaudal D homolog 2 (Drosophila) antibody
      • Bicaudal D homolog 2 antibody
      • Bicd2 antibody
      • BICD2_HUMAN antibody
      • Coiled coil protein BICD2 antibody
      • Cytoskeleton like bicaudal D protein homolog 2 antibody
      • Homolog of Drosophila bicaudal D antibody
      • KIAA0699 antibody
      • Protein bicaudal D homolog 2 antibody
      see all

    Anti-BICD2 antibody images

    • Lane 1: Staining of BICD2 in HeLa whole cell lysate immunoprecipitated using ab117799 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Lane 2: control IgG. Predicted band size : 94 kDa. Exposure time: 30 seconds.

    References for Anti-BICD2 antibody (ab117799)

    ab117799 has not yet been referenced specifically in any publications.

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