The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at 2-10 µg/mg of lysate.
Application notesIs unsuitable for WB.
FunctionMay play a role in the dynein-dynactin interactions on the surface of membranous organelles, by associating with these complexes. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex.
Sequence similaritiesBelongs to the BicD family.
DomainThe fourth coiled coil region is involved in Golgi targeting and in the interaction with DCTN2.
Post-translational modificationsPhosphorylated by NEK9 in vitro.
Cellular localizationGolgi apparatus. Cytoplasm > cytoskeleton. In interphase cells mainly localizes to the Golgi complex and colocalizes with dynactin at microtubule plus ends (By similarity). Its localization is dependent on microtubule morphology.
Cytoskeleton like bicaudal D protein homolog 2 antibody
Homolog of Drosophila bicaudal D antibody
Protein bicaudal D homolog 2 antibody
Anti-BICD2 antibody images
Immunoprecipitation - BICD2 antibody (ab117799)
Lane 1: Staining of BICD2 in HeLa whole cell lysate immunoprecipitated using ab117799 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
Lane 2: control IgG.
Predicted band size : 94 kDa.
Exposure time: 30 seconds.
References for Anti-BICD2 antibody (ab117799)
has not yet been referenced specifically in any publications.
Publishing research using ab117799? Please let us know so that we can cite the reference in this datasheet.
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