Overview

  • Product nameAnti-Bik antibody
    See all Bik primary antibodies
  • Description
    Rabbit polyclonal to Bik
  • SpecificityThis antibody is specific for Bik.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide mapping to the N-terminus of Human Bik.

  • Positive control
    • Jurkat cell lysate, mouse intestine and rat kidney tissue lysates.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab41716 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 2 - 4 µg/ml. Predicted molecular weight: 18 kDa.

Target

  • FunctionAccelerates programmed cell death. Binding to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.
  • DomainIntact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
  • Cellular localizationEndomembrane system. Around the nuclear envelope, and in cytoplasmic membranes.
  • Information by UniProt
  • Database links
  • Alternative names
    • Apoptosis inducer NBK antibody
    • BBC1 antibody
    • Bcl-2-interacting killer antibody
    • BCL2 interacting killer antibody
    • bhikhari antibody
    • BIK antibody
    • Bik-like killer protein antibody
    • BIK_HUMAN antibody
    • BIP 1 antibody
    • BiP1 antibody
    • BP 4 antibody
    • BP4 antibody
    • cb 60 antibody
    • NBK antibody
    see all

References for Anti-Bik antibody (ab41716)

ab41716 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"