Overview

  • Product nameAnti-Bik antibody
    See all Bik primary antibodies
  • Description
    Mouse monoclonal to Bik
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human, Recombinant Fragment
  • Immunogen

    Recombinant fragment: EDLDPMEDFD SLECMEGSDA LALRLACIGD EMDVSLRAPR LAQLSEVAMH SLGLAFIYDQ TEDIRDVLRS FMDGFTTLKE NIMRFWRSPN PGSWVSCEQV , corresponding to amino acids 37-136 of Human Bik

Properties

Applications

Our Abpromise guarantee covers the use of ab54862 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionAccelerates programmed cell death. Binding to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.
    • DomainIntact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
    • Cellular localizationEndomembrane system. Around the nuclear envelope, and in cytoplasmic membranes.
    • Information by UniProt
    • Database links
    • Alternative names
      • Apoptosis inducer NBK antibody
      • BBC1 antibody
      • Bcl-2-interacting killer antibody
      • BCL2 interacting killer antibody
      • bhikhari antibody
      • BIK antibody
      • Bik-like killer protein antibody
      • BIK_HUMAN antibody
      • BIP 1 antibody
      • BiP1 antibody
      • BP 4 antibody
      • BP4 antibody
      • cb 60 antibody
      • NBK antibody
      see all

    Anti-Bik antibody images

    • Bik antibody (ab54862) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human lung.
    • Western blot against tagged recombinant protein immunogen using ab54862 Bik antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa

    References for Anti-Bik antibody (ab54862)

    ab54862 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab54862.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"