Anti-Bile salt-activated lipase antibody (ab112940)

Overview

  • Product nameAnti-Bile salt-activated lipase antibody
    See all Bile salt-activated lipase primary antibodies
  • Description
    Rabbit polyclonal to Bile salt-activated lipase
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 453-482 of Human Bile salt-activated lipase (NP_001798.2).

  • Positive control
    • MDA-MB435 cell line lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab112940 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 79 kDa.

Target

  • RelevanceDefects in Bile salt activated lipase (CEL) are a cause of maturity onset diabetes of the young type 8 with exocrine dysfunction (MODY8) [MIM:609812], also known as diabetes and pancreatic exocrine dysfunction (DPED). MODY [MIM:606391] is an autosomal dominant form of diabetes mellitus. The pancreas serves both endocrine and exocrine functions. The endocrine cells are found in the islets of Langerhans. They synthesize insulin and other hormones, and are involved in the pathogenesis of diabetes mellitus. The exocrine cells produce bicarbonate and digestive enzymes and are involved in the pathogenesis of pancreatic malabsorption. The localization of the islets within exocrine pancreatic tissue is suggestive of an interdependency and cross talk between these two cell populations in their normal and in their abnormal function.
  • Cellular localizationCytoplasmic and Nuclear
  • Database links
  • Alternative names
    • BAL antibody
    • Bile salt-stimulated lipase antibody
    • BSDL antibody
    • BSSL antibody
    • Bucelipase antibody
    • Carboxyl ester lipase (bile salt stimulated lipase) antibody
    • Carboxyl ester lipase antibody
    • CEase antibody
    • CEL antibody
    • CELL antibody
    • Cholesterol esterase antibody
    • FAP antibody
    • FAPP antibody
    • Fetoacinar pancreatic protein antibody
    • LIPA antibody
    • Lysophospholipase, pancreatic antibody
    • MODY8 antibody
    • Pancreatic lysophospholipase antibody
    • Sterol esterase antibody
    see all

Anti-Bile salt-activated lipase antibody images

  • Anti-Bile salt-activated lipase antibody (ab112940) at 1/100 dilution + MDA-MB435 cell line lysates at 35 µg

    Predicted band size : 79 kDa

References for Anti-Bile salt-activated lipase antibody (ab112940)

ab112940 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your patience.

I received the alignment score from the laboratory for the immunogen of ab112940 with Zebrafish

Score = 20.2 bits (40), Expect = 9e-05

Identities = 9/14 (64%), Positives = 9/14 (64%), Gaps = 0/...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"