Overview

  • Product name
  • Description
    Rabbit polyclonal to BIRC6
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Rhesus monkey, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region between residues 4775 and the C-terminus (residue 4829) of Human BIRC6 (Swiss-Prot Q9NR09).

  • Positive control
    • Human ovarian tumor. Human metastatic lymph node.

Properties

Applications

Our Abpromise guarantee covers the use of ab84429 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.
    Likely to work with frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Protects cells from undergoing apoptosis.
    • Tissue specificity
      Expressed in brain cancer cells.
    • Sequence similarities
      In the C-terminal section; belongs to the ubiquitin-conjugating enzyme family.
      Contains 1 BIR repeat.
    • Post-translational
      modifications
      Ubiquitinated. Ubiquitination is mediated by the RNF41 E3 ligase and leads to proteasomal degradation, impairing inhibition of apoptosis.
    • Information by UniProt
    • Database links
    • Alternative names
      • Apollon antibody
      • Apollon protein antibody
      • Baculoviral IAP repeat containing 6 antibody
      • Baculoviral IAP repeat containing protein 6 antibody
      • Baculoviral IAP repeat-containing protein 6 antibody
      • BIR repeat containing ubiquitin conjugating enzyme antibody
      • BIRC 6 antibody
      • BIRC6 antibody
      • BIRC6_HUMAN antibody
      • BRUCE antibody
      • FLJ13726 antibody
      • FLJ13786 antibody
      • KIAA1289 antibody
      • Ubiquitin conjugating BIR domain enzyme apollon antibody
      • Ubiquitin-conjugating BIR domain enzyme apollon antibody
      see all

    Images

    • ab84429, at 1/250 dilution, staining BIRC6 in formalin-fixed, paraffin-embedded human ovarian tumor by Immunohistochemistry using DAB detection.
    • ab84429, at 1/250 dilution, staining BIRC6 in formalin-fixed, paraffin-embedded human metastatic lymph node by Immunohistochemistry using DAB detection.

    References

    This product has been referenced in:

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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