Overview

  • Product nameAnti-BLAP75 antibody
    See all BLAP75 primary antibodies
  • Description
    Rabbit polyclonal to BLAP75
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region between residue 275 and 300 of human BLAP75 (NP_079221.1)

  • Positive control
    • Human skin basal cell carcinoma tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab84387 was affinity purified using an epitope specific to BLAP75 immobilized on solid support.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab84387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionEssential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
    • Sequence similaritiesBelongs to the RMI1 family.
    • Cellular localizationNucleus. Forms foci in response to DNA damage.
    • Information by UniProt
    • Database links
    • Alternative names
      • BLAP75 antibody
      • BLM associated polypeptide 75 kDa antibody
      • BLM associated protein 75 kDa antibody
      • BLM-associated protein of 75 kDa antibody
      • C9orf76 antibody
      • FAAP75 antibody
      • FLJ12888 antibody
      • Homolog of yeast RecQ mediated genome instability 1 antibody
      • RecQ mediated genome instability 1 antibody
      • RecQ-mediated genome instability protein 1 antibody
      • Rmi1 antibody
      • RMI1 homolog antibody
      • RMI1 RecQ mediated genome instability 1 homolog antibody
      • RMI1_HUMAN antibody
      • RP11-346I8 antibody
      see all

    Anti-BLAP75 antibody images

    • ab84387, at 1/250 dilution, staining BLAP75 in formalin fixed, paraffin embedded human skin basal cell carcinoma tissue by Immunohistochemistry.
      Detection: DAB staining using anti-Rabbit IHC antibody at a dilution of 1/100.

    References for Anti-BLAP75 antibody (ab84387)

    ab84387 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"