Anti-BLMH antibody [2079C4a] (ab50988)

Overview

• Product name
  Anti-BLMH antibody [2079C4a]
  See all BLMH primary antibodies
• Description
  Mouse monoclonal [2079C4a] to BLMH
• Tested applications
  Suitable for: Dot blot, WBmore details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant fragment (Human)

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
• Storage buffer
  Preservative: 0.05% Sodium Azide
  Constituents: 1% BSA, PBS, pH 7.4
• Concentration information loading...
• Purity
  Protein G purified
• Purification notes
  Filtered through a 0.22 µm membrane.
• Clonality
  Monoclonal
• Clone number
  2079C4a
• Isotype
  IgG2b
• Research areas
  • Neuroscience
  • Neurology process
  • Neurodegenerative disease
  • Alzheimer's disease
  • Other

  • Neuroscience
  • Neurology process
  • Neurodegenerative disease
  • Other

  • Cell Biology
  • Proteolysis / Ubiquitin
  • Proteolytic enzymes
  • Other proteases

Associated products

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

Applications

Target

• Function
  The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity.
• Sequence similarities
  Belongs to the peptidase C1 family.
• Cellular localization
  Cytoplasm.

• Target information above from: UniProt accession Q13867 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 642 Human
  • Omim: 602403 Human
  • SwissProt: Q13867 Human
  • Unigene: 371914 Human
• Alternative names
  • BH antibody
  • Bleomycin hydrolase antibody
  • BLM hydrolase antibody

  • BLMH antibody
  • BLMH_HUMAN antibody
  • BMH antibody
  • EC 3.4.22.40 antibody

  see all

Protocols

• Western blot protocols