Overview

  • Product name
  • Description
    Rabbit polyclonal to BLOC1S2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Horse, Chicken, Cow, Cat, Dog, Human, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 31-80 (KEPAEADINE LCRDMFSKMA TYLTGELTAT SEDYKLLENM NKLTSLKYLE) of Mouse BLOC1S2 (NP_082883).

  • Positive control
    • Mouse heart lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab125506 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 16 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    May play a role in cell proliferation. The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking.
  • Tissue specificity
    Isoform 1 and isoform 2 are widely expressed. Expressed in various malignant tumor tissues (at protein level).
  • Sequence similarities
    Belongs to the BLOC1S2 family.
  • Cellular localization
    Cytoplasm > cytoskeleton > centrosome. Localizes to the centrosomes in a microtubule-dependent manner.
  • Information by UniProt
  • Database links
  • Alternative names
    • Biogenesis of lysosome-related organelles complex 1 subunit 2 antibody
    • BL1S2_HUMAN antibody
    • BLOC-1 subunit 2 antibody
    • Bloc1s2 antibody
    • BLOS2 antibody
    • Centrosome-associated protein antibody
    • RP11 316M21.4 antibody
    see all

Images

  • Anti-BLOC1S2 antibody (ab125506) at 1 µg/ml + Mouse heart lysate at 10 µg

    Secondary
    Goat anti-Rabbit IgG-HRP

    Predicted band size : 16 kDa

References

ab125506 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab125506.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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