Our Stem Cells team have put together a fantastic overview of stem cell fate during embryonic development. Differentiation of stem cells to a lineage-committed fate can be monitored by molecular marker expression, so this pathway card will be a handy reference tool for identifying prominent markers.
Also on the card, we've picked out a selection of our antibodies suitable for characterization, based on those with the broadest range of applications. Here's two of them, each with great images.
A homolog of the Drosophila protein VASA, DEAD-box protein 4 (DDX4) is a germline marker expressed only in the ovary and testis. DDX4 is expressed in spermatogenic cells from the spermatocyte stage to the round spermatid stage and in migratory primordial germ cells in the region of the gonadal ridge in both sexes.
ICC/IF, IHC-FoFr, IHC-Fr, IHC-P, WB
Hu, Ms, Rat, Cow, Pig
23 references, four customer reviews, average five star rating
Olig2 (oligodendrocyte transcription factor 2) is required for oligodendrocyte and motor
neuron specification in the spinal cord, as well as for the development of somatic motor
neurons in the hindbrain.Tested applications
ICC/IF, IHC (PFA fixed), IHC-FoFr, IHC-Fr, IHC-P, WB
One reference, nine customer reviews, average four star rating
We have nearly 600 lineage markers in our catalog, for a wide range of applications and many with excellent customer reviews and images, be sure to check out the full range.
For a complete listing of all the free posters and pathways available from Abcam, check out the poster library at www.abcam.com/posters
I hope you find our pathways useful for your research, let me know what you think!