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Abcam Events | 10th Anniversary give-away

Four lucky winners will be given free registration and all-inclusive accommodation to either Chromatin: Structure & Function 2015 (November 16-19, 2015 - Grand Caymans) or Maintenance of Genome Stability 2016 (March 7-10, 2016 - Panama).

To be in with a chance of winning, all you have to do is to provide a few details to enter our prize drawing before December 13, 2014.

Enter give-away »

 

Epigenetics and memory

Memories of our first day at school or trips to exciting places are a vital part of making us who we are. But how are we able to remember events that happened so long ago?

Over the last few years, research has shed light on some of the mechanisms involved in memory formation, and it seems as though epigenetics may have a big part to play.

Read more»

 

Top epigenetics articles | October 2014

So many journals, so little time. Read our handpicked selection of the most exciting epigenetics research papers from the past month.

This month, the role of polycomb-mediated epigenetics in the formation of subcerebral projection neurons, using CRISPR-Cas9 to knock down DNA methyltransferases in the mouse brain and how DNA methylation influences heart development and disease.

View our October selection»

 

Scientist of the month | interview with Professor Sir John Gurdon

Our scientist of the month for October is Professor Sir John Gurdon of the Gurdon Institute in Cambridge. He shares with us his thoughts on the future of epigenetics and what winning the Nobel Prize meant to him.

Read the full interview»

 

Protocols for IHC and ICC/IF that you can trust

Are you new to immunohistochemistry or immunofluorescence? Have you thought of trying a new immunostaining method but don't know where to start? To help your research take off, we've collected all our IHC and ICC/IF know-how into a comprehensive protocols page covering among other topics:

Browse IHC and ICC/IF protocols»

 

Choose the right markers for your neuronal subset

Mining information on which proteins can serve as markers for specific neuronal subtypes can be time consuming.

To save you precious time and effort, we have created a series of articles showcasing the most widely used markers for the study of neurons, covering everything from neuroepithelial cells to mature neurons and from glutamatergic to cholinergic cells.

Find the right marker for you experiment»

 

The role of Polycomb group proteins in cancer | free webinar

Let our guest speaker Dr. Adrian Bracken introduce you to Polycomb group (PcG) proteins and their role in cancer.

Our speaker will cover the following points:

  • Introduction to Polycombs and their importance in developmental and stem cell biology
  • Connections between Polycombs and cancer: the INK4A and DNA methylation links
  • The NGS revolution: Polycombs are both oncogenes and tumour suppressors
  • Future cancer therapy and perspectives

Register now»

 

Tips and tricks to get your ChIP experiments working

To help you to get your ChIP experiments underway, we have brought some useful ChIP tips and tricks together in three articles that will make your experiments work first time and can be found on our epigenetics resources page.

  • If you want some help before you begin, the ChIP tips and tricks article, compiled by Dr Andy Bannister from the Gurdon Institute, will guide you through useful tips for a successful experiment.
  • If you are dealing with small sample sizes, have a look at our article on advances in ChIP-seq analysis with small samples for advice on the latest advances in ChIP-seq analysis.
  • If you are having trouble with high background, poor resolution or low signal, our ChIP troubleshooting guide will give you fixes to solve common ChIP problems.

View all epigenetics resources»

 

Top epigenetics articles | September 2014

Too busy in the lab to keep on top of the latest epigenetics literature? Sit back and read our top picks from September.

Highlights of this month include how removal of the vernalized state in plants is achieved by epigenetic reprogramming, a role of histone variants in memory formation and advances in predicting epigenomes by studying DNA motifs.

View our September selection»

 

Free updated IHC application guide now available

There's a lot to think about when planning an IHC experiment, from what controls to use to which detection method is best. To support you, we gathered must-have IHC tips and tricks and updated our extensive IHC application guide. It covers the key steps and variables that you need to consider. These include:

  • Sample preparation
  • Antigen retrieval
  • Tissue permeabilization
  • Blocking and immunostaining
  • Key reagents

Get our IHC application guide»

 

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