Anti-Blood Group Antigen Precursor antibody (ab175029)

Overview

  • Product name
    Anti-Blood Group Antigen Precursor antibody
    See all Blood Group Antigen Precursor primary antibodies
  • Description
    Rabbit polyclonal to Blood Group Antigen Precursor
  • Tested applications
    Suitable for: ICC/IF, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant full length protein corresponding to Human Blood Group Antigen Precursor.
    Database link: P16442

  • Positive control
    • 293T cell extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab175029 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.
IHC-P 1/50 - 1/200.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

WB 1/500 - 1/2000. Predicted molecular weight: 41 kDa.

Target

  • Function
    This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
  • Pathway
    Protein modification; protein glycosylation.
  • Sequence similarities
    Belongs to the glycosyltransferase 6 family.
  • Domain
    The conserved DXD motif is involved in cofactor binding. The manganese ion interacts with the beta-phosphate group of UDP and may also have a role in catalysis.
  • Post-translational
    modifications
    The soluble form derives from the membrane form by proteolytic processing.
  • Cellular localization
    Golgi apparatus > Golgi stack membrane. Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
  • Information by UniProt
  • Database links
  • Alternative names
    • A transferase antibody
    • A3GALNT antibody
    • A3GALT1 antibody
    • ABO A3 transferase antibody
    • Abo antibody
    • ABO blood group (transferase A alpha 1-3 N acetylgalactosaminyltransferase transferase B alpha 1 3 galactosyltransferase) antibody
    • ABO glycosyltransferase antibody
    • ABO weak transfer antibody
    • B (A) alpha 1, 3 glactosyltransferase antibody
    • B transferase antibody
    • BGAT_HUMAN antibody
    • Fucosylglycoprotein 3 alpha galactosyltransferase antibody
    • Fucosylglycoprotein 3-alpha-galactosyltransferase antibody
    • Fucosylglycoprotein alpha N acetylgalactosaminyltransferase antibody
    • Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase antibody
    • Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form antibody
    • Glycoprotein fucosylgalactoside alpha galactosyltransferase antibody
    • Glycoprotein fucosylgalactoside alpha N acetylgalactosaminyltransferase antibody
    • Glycoprotein-fucosylgalactoside alpha-galactosyltransferase antibody
    • Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase antibody
    • GTB antibody
    • Histo blood group A transferase antibody
    • Histo blood group A2 transferase antibody
    • Histo blood group ABO system transferase antibody
    • Histo blood group B transferase antibody
    • Histo-blood group A transferase antibody
    • Histo-blood group B transferase antibody
    • NAGAT antibody
    see all

References

ab175029 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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