Recombinant
RabMAb

Anti-Blood Group Antigen Precursor antibody [EPR6205] (ab126612)

Overview

  • Product name
    Anti-Blood Group Antigen Precursor antibody [EPR6205]
    See all Blood Group Antigen Precursor primary antibodies
  • Description
    Rabbit monoclonal [EPR6205] to Blood Group Antigen Precursor
  • Tested applications
    Suitable for: WB, IPmore details
    Unsuitable for: Flow Cyt,ICC/IF or IHC-P
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, corresponding to residues near the N-terminus of Human Blood Group Antigen Precursor.

  • Positive control
    • Human fetal lung lysate, fetal kidney and 293T lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab126612 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 41 kDa.
IP 1/10 - 1/100.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
  • Target

    • Function
      This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
    • Pathway
      Protein modification; protein glycosylation.
    • Sequence similarities
      Belongs to the glycosyltransferase 6 family.
    • Domain
      The conserved DXD motif is involved in cofactor binding. The manganese ion interacts with the beta-phosphate group of UDP and may also have a role in catalysis.
    • Post-translational
      modifications
      The soluble form derives from the membrane form by proteolytic processing.
    • Cellular localization
      Golgi apparatus > Golgi stack membrane. Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
    • Information by UniProt
    • Database links
    • Alternative names
      • A transferase antibody
      • A3GALNT antibody
      • A3GALT1 antibody
      • ABO A3 transferase antibody
      • Abo antibody
      • ABO blood group (transferase A alpha 1-3 N acetylgalactosaminyltransferase transferase B alpha 1 3 galactosyltransferase) antibody
      • ABO glycosyltransferase antibody
      • ABO weak transfer antibody
      • B (A) alpha 1, 3 glactosyltransferase antibody
      • B transferase antibody
      • BGAT_HUMAN antibody
      • Fucosylglycoprotein 3 alpha galactosyltransferase antibody
      • Fucosylglycoprotein 3-alpha-galactosyltransferase antibody
      • Fucosylglycoprotein alpha N acetylgalactosaminyltransferase antibody
      • Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase antibody
      • Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form antibody
      • Glycoprotein fucosylgalactoside alpha galactosyltransferase antibody
      • Glycoprotein fucosylgalactoside alpha N acetylgalactosaminyltransferase antibody
      • Glycoprotein-fucosylgalactoside alpha-galactosyltransferase antibody
      • Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase antibody
      • GTB antibody
      • Histo blood group A transferase antibody
      • Histo blood group A2 transferase antibody
      • Histo blood group ABO system transferase antibody
      • Histo blood group B transferase antibody
      • Histo-blood group A transferase antibody
      • Histo-blood group B transferase antibody
      • NAGAT antibody
      see all

    Images

    • All lanes : Anti-Blood Group Antigen Precursor antibody [EPR6205] (ab126612) at 1/1000 dilution

      Lane 1 : Human fetal lung lysate
      Lane 2 : 293T lysate
      Lane 3 : Human fetal kidney lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      Goat Anti-rabbit HRP at 1/2000 dilution

      Predicted band size : 41 kDa

    References

    ab126612 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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