Anti-Blood Group Lewis a antibody [SPM522], prediluted (ab64099)

Overview

  • Product nameAnti-Blood Group Lewis a antibody [SPM522], prediluted
    See all Blood Group Lewis a primary antibodies
  • Description
    Mouse monoclonal [SPM522] to Blood Group Lewis a, prediluted
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Mucin isolated from an ovarian cyst.

  • EpitopeGal Beta1-3(Fuc alpha1-4) GlcNAc
  • Positive control
    • Human Colon carcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab64099 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: Ready-to-use for 30 min at Room temperature. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.



    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceLewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
    • Cellular localizationCytoplasmic
    • Alternative names
      • Lewis A antigen antibody

    Anti-Blood Group Lewis a antibody [SPM522], prediluted images

    • ab64099 staining Blood Group Lewis a in human colon carcinoma tissue by immunohistochemistry on formalin-fixed, paraffin-embedded tissue.

    References for Anti-Blood Group Lewis a antibody [SPM522], prediluted (ab64099)

    This product has been referenced in:
    • Hamada E  et al. Investigation of unexpected serum CA19-9 elevation in Lewis-negative cancer patients. Ann Clin Biochem 49:266-72 (2012). Read more (PubMed: 22492877) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab64099.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"