Anti-Blood Group Tn Antigen antibody [Tn 218] (ab115949)

Overview

  • Product nameAnti-Blood Group Tn Antigen antibody [Tn 218]
    See all Blood Group Tn Antigen primary antibodies
  • Description
    Mouse monoclonal [Tn 218] to Blood Group Tn Antigen
  • Tested applicationsSuitable for: IHC-P, IHC-Fr, ICCmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Asialo Sheep (Ovine) submaxillary mucin (AOSM).

  • EpitopeAlpha GalNacOSer/Thr.
  • Positive control
    • Human epithelial carcinoma, pancreatic, colon, stomach and breast tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab115949 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
IHC-Fr 1/50 - 1/100.
ICC 1/50 - 1/100.

Target

  • RelevanceThe cryptantigen Tn is found on Glycophorin A and B in humans. Found on haemopoietic cells associated with polyagglutination, thrombocytopenia and/or leucopenia. Tn has been detected prior to onset of leukemia and may be a useful tumour marker, reacting with breast carcinoma and adenocarcinoma cells.
  • Cellular localizationMembrane; Single-pass type I membrane protein.

References for Anti-Blood Group Tn Antigen antibody [Tn 218] (ab115949)

ab115949 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"