Anti-Blood Group Tn Antigen antibody [Tn 218] (ab115949)

Overview

  • Product name
    Anti-Blood Group Tn Antigen antibody [Tn 218]
    See all Blood Group Tn Antigen primary antibodies
  • Description
    Mouse monoclonal [Tn 218] to Blood Group Tn Antigen
  • Tested applications
    Suitable for: IHC-P, IHC-Fr, ICCmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Asialo Sheep (Ovine) submaxillary mucin (AOSM).

  • Epitope
    Alpha GalNacOSer/Thr.
  • Positive control
    • Human epithelial carcinoma, pancreatic, colon, stomach and breast tissues.
  • General notes

    This product was changed from ascites to tissue culture supernatant on 15th June 2017.  The following lots are from ascites and still in stock as of 15th June 2017 (GR246503-10, GR246503-11, GR246503-12).  Lot numbers higher than GR246503-12 will be from tissue culture supernatant.  Please note that the dilutions may need to be adjusted accordingly.

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June 2019 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause.

Properties

Applications

Our Abpromise guarantee covers the use of ab115949 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
IHC-Fr 1/50 - 1/100.
ICC 1/50 - 1/100.

Use at an assay dependent concentration

Target

  • Relevance
    The cryptantigen Tn is found on Glycophorin A and B in humans. Found on haemopoietic cells associated with polyagglutination, thrombocytopenia and/or leucopenia. Tn has been detected prior to onset of leukemia and may be a useful tumour marker, reacting with breast carcinoma and adenocarcinoma cells.
  • Cellular localization
    Membrane; Single-pass type I membrane protein.

References

ab115949 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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