Overview

  • Product name
  • Description
    Goat polyclonal to BLVRB
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Synthetic peptide corresponding to Human BLVRB aa 38-49 (internal sequence) (Cysteine residue). (NP_000704.1).
    Sequence:

    SRLPSEGPRPAH


    Database link: P30043

  • Positive control
    • Human liver lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.3
    Preservative: 0.02% Sodium azide
    Constituents: 0.5% BSA, 99% Tris buffer
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab188108 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab188108 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 23 kDa (predicted molecular weight: 22 kDa).

Target

  • Function
    Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.
  • Tissue specificity
    Predominantly expressed in liver and erythrocytes. At lower levels in heart, lung, adrenal gland and cerebrum.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Biliverdin IX beta reductase antibody
    • biliverdin reductase B (flavin reductase (NADPH)) antibody
    • Biliverdin reductase B antibody
    • Biliverdin-IX beta-reductase antibody
    • BLVRB antibody
    • BLVRB_HUMAN antibody
    • BVR B antibody
    • BVR-B antibody
    • BVRB antibody
    • epididymis secretory protein Li 10 antibody
    • Flavin reductase (NADPH) antibody
    • Flavin reductase antibody
    • FLR antibody
    • FR antibody
    • GHBP antibody
    • Green heme binding protein antibody
    • Green heme-binding protein antibody
    • HEL-S-10 antibody
    • Methemoglobin reductase antibody
    • MGC117413 antibody
    • NADPH dependent diaphorase antibody
    • NADPH flavin reductase antibody
    • NADPH-dependent diaphorase antibody
    • NADPH-flavin reductase antibody
    • SDR43U1 antibody
    • short chain dehydrogenase/reductase family 43U, member 1 antibody
    see all

Images

  • Anti-BLVRB antibody (ab188108) at 0.1 µg/ml + Human liver lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 22 kDa
    Observed band size : 23 kDa (why is the actual band size different from the predicted?)

    Primary incubation was 1 hour.

References

ab188108 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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