Overview

  • Product name
    Anti-BMP6 antibody [EPR7241]
    See all BMP6 primary antibodies
  • Description
    Rabbit monoclonal [EPR7241] to BMP6
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, ICC, IHC-P, Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human BMP6 (P22004)

  • Positive control
    • Saos-2 or fetal brain lysate, Human tonsil or Mouse liver tissue, permeabilized Saos-2 cells.
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab155963 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 42 kDa.
ICC 1/100 - 1/250.
IHC-P 1/100 - 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Flow Cyt 1/10 - 1/100.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

Target

  • Function
    Induces cartilage and bone formation.
  • Sequence similarities
    Belongs to the TGF-beta family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • BMP-6 antibody
    • Bmp6 antibody
    • BMP6_HUMAN antibody
    • Bone morphogenetic protein 6 antibody
    • Bone Morphogenic Protein 6 antibody
    • Decapentaplegic vegetal related antibody
    • DVR6 antibody
    • HGNC:12686 antibody
    • TGFB related vegetal related growth factor antibody
    • Transforming growth factor beta antibody
    • Vegetal related (TGFB related) cytokine antibody
    • Vegetal related growth factor (TGFB related) antibody
    • Vg related sequence antibody
    • VG-1-R antibody
    • VG-1-related protein antibody
    • Vg1 related sequence antibody
    • VGR antibody
    • VGR-1 antibody
    • VGR1 antibody
    see all

Images

  • All lanes : Anti-BMP6 antibody [EPR7241] (ab155963) at 1/1000 dilution

    Lane 1 : Saos-2 lysate
    Lane 2 : Fetal brain lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

    Predicted band size: 42 kDa

  • Immunohistochemical analysis of paraffin embedded Human tonsil tissue labeling BMP6 with ab155963 at a 1/100 dilution.
  • Immunohistochemical analysis of paraffin embedded Mouse liver tissue labeling BMP6 with ab155963 at a 1/100 dilution.
  • Flow cytometry analysis of permeabilized Saos-2 cells using ab155963 at a 1/10 dilution (red) or a rabbit IgG (negative) (green).

References

This product has been referenced in:
  • Liang Y  et al. Increased bone morphogenetic protein-6 in follicular fluid and granulosa cells may correlate with fertilization and embryo quality in humans. Exp Ther Med 14:1171-1176 (2017). Read more (PubMed: 28810575) »
  • Liu G  et al. Reduced BMP6 expression by DNA methylation contributes to EMT and drug resistance in breast cancer cells. Oncol Rep 32:581-8 (2014). Read more (PubMed: 24890613) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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