Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab35086 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
  • Application notes
    ELISA: 1/40 - 1/200. Using antibody at 1/200 dilution in competative ELISA, 1µg per well of BSA-conjugated peptide gives some displacment in the range 0.5 to 1000 µg/ml (max 20%). This might be improved by using lower dilutions (<1/50) or by using an antibody affinity purified on a peptide column.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
    • Tissue specificity
      Expressed in the kidney and bladder. Lower levels seen in the brain.
    • Sequence similarities
      Belongs to the TGF-beta family.
    • Developmental stage
      Expressed in the developing eye, brain and ear during embryogenesis.
    • Post-translational
      modifications
      Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (PubMed:17977014).
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • BMP 7 antibody
      • BMP-7 antibody
      • Bmp7 antibody
      • BMP7_HUMAN antibody
      • Bone morphogenetic protein 7 antibody
      • Bone morphogenic protein 7 antibody
      • Eptotermin alfa antibody
      • OP 1 antibody
      • OP-1 antibody
      • OP1 antibody
      • Osteogenic protein 1 antibody
      see all

    References for Anti-BMP7 antibody (ab35086)

    ab35086 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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