Overview

  • Product name
  • Description
    Rabbit polyclonal to BMP7
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Rat, Chicken, Human
  • Immunogen

    Synthetic peptide corresponding to Human BMP7 (C terminal).
    Database link: NM_001719

  • Positive control
    • Rat kidney tissue; Human kidney cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab93636 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
  • Application notes
    IHC-P: 1/50 - 1/200.
    WB: 1/200 - 1/1000. Predicted molecular weight: 49 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
    • Tissue specificity
      Expressed in the kidney and bladder. Lower levels seen in the brain.
    • Sequence similarities
      Belongs to the TGF-beta family.
    • Developmental stage
      Expressed in the developing eye, brain and ear during embryogenesis.
    • Post-translational
      modifications
      Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (PubMed:17977014).
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • BMP 7 antibody
      • BMP-7 antibody
      • Bmp7 antibody
      • BMP7_HUMAN antibody
      • Bone morphogenetic protein 7 antibody
      • Bone morphogenic protein 7 antibody
      • Eptotermin alfa antibody
      • OP 1 antibody
      • OP-1 antibody
      • OP1 antibody
      • Osteogenic protein 1 antibody
      see all

    Anti-BMP7 antibody images

    • ab93636, at 1/100 dilution, staining secreted BMP7 in formalin-fixed, paraffin-embedded rat kidney tissue by Immunohistochemistry.
    • Anti-BMP7 antibody (ab93636) at 1/200 dilution + Human kidney cell lysate

      Predicted band size : 49 kDa

    References for Anti-BMP7 antibody (ab93636)

    This product has been referenced in:
    • Zhang Y  et al. Effects of imposed defocus of opposite sign on temporal gene expression patterns of BMP4 and BMP7 in chick RPE. Exp Eye Res 109:98-106 (2013). Read more (PubMed: 23428741) »

    See 1 Publication for this product

    Product Wall

    Thank you for contacting us.

    The lab let me know that this antibody was raised against a peptide from near the C terminal residues of human BMP-7 protein (within residues 200-400).

    I hope this information is helpful to you. Please...

    Read More
    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application
    Western blot
    Sample
    Chicken Tissue lysate - whole (retina, RPE, choroid)
    Loading amount
    20 µg
    Specification
    retina, RPE, choroid
    Gel Running Conditions
    Reduced Denaturing (NuPAGE 4-12% Bis-Tris Gel)
    Blocking step
    (agent) for 30 minute(s) · Concentration: 100% · Temperature: 25°C
    Username

    Yan Zhang

    Verified customer

    Submitted Feb 28 2012

    Thank you for contacting Abcam. As you have requested, I have changed the status of your abreviews for ab6285 (abreview xxxx) and ab93939 (abreview xxxx) to an editing stage. This way you will be able to go back into those and change the information...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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