Recombinant
RabMAb

Anti-BMP8b antibody [EPR13357] (ab181253)

Overview

  • Product name
    Anti-BMP8b antibody [EPR13357]
    See all BMP8b primary antibodies
  • Description
    Rabbit monoclonal [EPR13357] to BMP8b
  • Specificity
    This antibody detects dominant ~35kDa extra band in some samples, e.g. WI-38 and SK-OV-3.
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human BMP8b aa 350 to the C-terminus. The exact sequence is proprietary.
    Database link: P34820

  • Positive control
    • HeLa and A549 cell lysate; A549 cells.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab181253 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).
ICC/IF 1/250.

Target

  • Function
    Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
  • Sequence similarities
    Belongs to the TGF-beta family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • BMP-8 antibody
    • BMP-8B antibody
    • BMP8 antibody
    • Bmp8b antibody
    • BMP8B_HUMAN antibody
    • bone morphogenetic protein 8 (osteogenic protein 2) antibody
    • Bone morphogenetic protein 8 antibody
    • Bone morphogenetic protein 8B antibody
    • dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)) antibody
    • OP-2 antibody
    • OP2 antibody
    • Osteogenic protein 2 antibody
    see all

Images

  • All lanes : Anti-BMP8b antibody [EPR13357] (ab181253) at 1/1000 dilution

    Lane 1 : HeLa cell lysate
    Lane 2 : A549 cell lysate

    Lysates/proteins at 20 µg per lane.

    Secondary
    goat anti-rabbit IgG, (H+L), peroxidase conjugated at 1/1000 dilution
    Developed using the ECL technique

    Predicted band size : 45 kDa
    Observed band size : 45 kDa
  • Immunofluorescence analysis of, paraformaldehyde-fixed, A549 cells labeling BMP8b with ab181253 at a 1/250 dilution. As secondary antibody goat anti rabbit IgG (Alexa Fluor®488) was used at a 1/200 dilution. In blue DAPI staining.

References

ab181253 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab181253.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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