Overview

  • Product nameAnti-BMP9 antibody
    See all BMP9 primary antibodies
  • Description
    Rabbit polyclonal to BMP9
  • Tested applicationsSuitable for: WB, IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide from the N-terminal region of human BMP9 conjugated to KLH

  • Positive control
    • Mouse liver tissue lysate and human hepatocellular carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab71809 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Detects a band of approximately 50 kDa (predicted molecular weight: 47 kDa).
IHC-P 1/50 - 1/100.
ELISA 1/1000.

Target

  • RelevanceBMP9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. They are regulators of cell growth and differentiation. BMP9 has a role in the maturation of BFCN (basal forebrain cholinergic neurons) also inducing and maintaining the ability of these cells to respond to acetylcholine; BFCN are important for the processes of learning, memory and attention. BMP9 is a potent inducer of hepcidin (a cationic peptide that has a antimicrobial properties) in hepatocytes and can regulate iron metabolism. The physiological receptor of BMP9 is thought to be activin receptor-like kinase 1, ALK1 (also called ACVRL1), an endothelial-specific type I receptor of the TGF-beta receptor family. BMP9 is one of the most potent BMPs to induce orthotopic bone formation in vivo. BMP3, a blocker of most BMPs seems not to affect BMP9.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • BMP 9 antibody
    • Bone morphogenetic protein 9 antibody
    • GDF 2 antibody
    • GDF2 antibody
    • growth differentiation factor 2 antibody
    • Growth/differentiation factor 2 antibody
    see all

Anti-BMP9 antibody images

  • Anti-BMP9 antibody (ab71809) at 1/100 dilution + mouse liver tissue lysate at 12.5 µg

    Predicted band size : 47 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)
  • ab71809 at 1/50 dilution, staining BMP9 in human hepatocarcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and DAB staining.

References for Anti-BMP9 antibody (ab71809)

ab71809 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"