• Product nameAnti-BMPR1B antibody
    See all BMPR1B primary antibodies
  • Description
    Rabbit polyclonal to BMPR1B
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 141-168 of Human BMPR1B (NP_001194.1).

  • Positive control
    • U251 cell line lysates.



Our Abpromise guarantee covers the use of ab110955 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 57 kDa.


  • FunctionOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5.
  • Involvement in diseaseDefects in BMPR1B are the cause of acromesomelic chondrodysplasia with genital anomalies (AMDGA) [MIM:609441]. Acromesomelic chondrodysplasias are rare hereditary skeletal disorders characterized by short stature, very short limbs, and hand/foot malformations. The severity of limb abnormalities increases from proximal to distal with profoundly affected hands and feet showing brachydactyly and/or rudimentary fingers (knob-like fingers).
    Defects in BMPR1B are a cause of brachydactyly type A2 (BDA2) [MIM:112600]. Brachydactylies (BDs) are a group of inherited malformations characterized by shortening of the digits due to abnormal development of the phalanges and/or the metacarpals. They have been classified on an anatomic and genetic basis into five groups, A to E, including three subgroups (A1 to A3) that usually manifest as autosomal dominant traits. BDA2 was described first in a large Norwegian kindred. BDA2 is caused by mutations in BMPR1B gene and studies demonstrate that these mutations function as dominant negatives in vitro and in vivo.
  • Sequence similaritiesBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 GS domain.
    Contains 1 protein kinase domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activin receptor like kinase 6 antibody
    • Acvrlk6 antibody
    • ALK 6 antibody
    • ALK6 antibody
    • alk6tr antibody
    • BMP type-1B receptor antibody
    • BMPR IB antibody
    • BMPR-1B antibody
    • Bmpr1b antibody
    • BMPRIB antibody
    • BMR1B_HUMAN antibody
    • Bone morphogenetic protein receptor type 1B antibody
    • Bone morphogenetic protein receptor type IB antibody
    • Bone morphogenetic protein receptor type-1B antibody
    • BR 1b antibody
    • BR1b antibody
    • CDw 293 antibody
    • CDw293 antibody
    • CDw293 antigen antibody
    • CFK 43a antibody
    • CFK43a antibody
    • Serine/threonine receptor kinase antibody
    • zALK 6 antibody
    • zALK6 antibody
    see all

Anti-BMPR1B antibody images

  • Anti-BMPR1B antibody (ab110955) at 1/100 dilution + U251 cell line lysates at 35 µg

    Predicted band size : 57 kDa

References for Anti-BMPR1B antibody (ab110955)

ab110955 has not yet been referenced specifically in any publications.

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