The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesELISA: Use at an assay dependent dilution.
ICC: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
WB: Use at a concentration of 2 - 4 µg/ml. Predicted molecular weight: 22 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionApoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2.
Sequence similaritiesBelongs to the NIP3 family.
Cellular localizationMitochondrion. Mitochondrion membrane. Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Colocalizes with ACAA2 in the mitochondria.
BCL2 Adenovirus E1B 19kDa Interacting Protein 3 antibody
BCL2/adenovirus E1B 19 kDa protein interacting protein 3 antibody
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 antibody
BNIP 3 antibody
NIP 3 antibody
References for Anti-BNIP3 antibody [ANa40] (ab88729)
This product has been referenced in:
Chaanine AH et al. JNK modulates FOXO3a for the expression of the mitochondrial death and mitophagy marker BNIP3 in pathological hypertrophy and in heart failure. Cell Death Dis3:265 (2012).
Read more (PubMed: 22297293) »