Overview

  • Product nameAnti-BNIP3L antibody [ZN002]
    See all BNIP3L primary antibodies
  • Description
    Mouse monoclonal [ZN002] to BNIP3L
  • Specificityab54298 is specific for the BNIP3L protein.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide derived from the internal region of human, mouse and rat BNIP3L proteins

  • Positive control
    • Human K562 and mouse P3 myeloma cell lysates.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab54298 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 40 kDa (predicted molecular weight: 24 kDa).
ELISA Use a concentration of 0.1 - 1 µg/ml.

Target

  • FunctionInduces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. May function as a tumor suppressor. Inhibits apoptosis induced by BNIP3.
  • Sequence similaritiesBelongs to the NIP3 family.
  • Post-translational
    modifications
    Undergoes progressive proteolysis to an 11 kDa C-terminal fragment, which is blocked by the proteasome inhibitor lactacystin.
  • Cellular localizationNucleus envelope. Endoplasmic reticulum. Mitochondrion. Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Adenovirus E1B19k binding protein B5 antibody
    • Adenovirus E1B19K-binding protein B5 antibody
    • BCL2/adenovirus E1B 19 kd protein interacting protein 3a antibody
    • BCL2/adenovirus E1B 19 kDa protein interacting protein 3A antibody
    • BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like antibody
    • BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A antibody
    • BCL2/adenovirus E1B 19kDa interacting protein 3 like antibody
    • BNI3L_HUMAN antibody
    • BNIP3a antibody
    • BNIP3H antibody
    • BNIP3L antibody
    • BNIP3L protein antibody
    • NIP3 like protein X antibody
    • NIP3-like protein X antibody
    • NIP3L antibody
    • NIX antibody
    see all

Anti-BNIP3L antibody [ZN002] images

References for Anti-BNIP3L antibody [ZN002] (ab54298)

ab54298 has not yet been referenced specifically in any publications.

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