• Product nameAnti-BNP antibody
    See all BNP primary antibodies
  • Description
    Rabbit polyclonal to BNP
  • SpecificityCross-reactivity to other pepertides: Human Atrial Natriuretic Peptide 0% Rat Atrial Natriuretic Peptide 0% ACTH (human, 1-39) 0% Vasoactive Intestinal Peptide (VIP) 0%
  • Tested applicationsSuitable for: IHC-P, ELISA, RIA, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (Human) conjugated to bovine thyroglobulin.



Our Abpromise guarantee covers the use of ab19646 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
RIA Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.


  • RelevanceBrain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides). BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • BNP(1-28) antibody
    • BNP(1-29) antibody
    • BNP(1-30) antibody
    • BNP(1-32) antibody
    • BNP(2-31) antibody
    • BNP(3-29) antibody
    • BNP(3-30) antibody
    • BNP(3-32) antibody
    • BNP(4-27) antibody
    • BNP(4-29) antibody
    • BNP(4-30) antibody
    • BNP(4-31) antibody
    • BNP(4-32) antibody
    • BNP(5-29) antibody
    • BNP(5-31) antibody
    • BNP(5-32) antibody
    • Brain natriuretic peptide 32 antibody
    • Brain type natriuretic peptide antibody
    • Gamma brain natriuretic peptide antibody
    • Natriuretic peptide B antibody
    • Natriuretic peptide precursor B antibody
    • natriuretic peptide, brain type antibody
    • Natriuretic peptides B antibody
    • natriuretic protein antibody
    • NPPB antibody
    see all

References for Anti-BNP antibody (ab19646)

This product has been referenced in:

See 1 Publication for this product

Product Wall

Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (iCell® Cardiomyocytes)
Permeabilization No
Specification iCell® Cardiomyocytes
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Fixative Acetone

Abcam user community

Verified customer

Submitted Aug 31 2015

Application Flow Cytometry
Fixation Acetone
Permeabilization No
Sample Human Cell (iCell­ Cardiomyocytes)
Specification iCell­ Cardiomyocytes
Gating Strategy negative control cells
Preparation Cell harvesting/tissue preparation method: 1 mM EDTA/1 mM EGTA in PBS (calcium- and magnesium-free)
Sample buffer: DPBS

Abcam user community

Verified customer

Submitted Feb 13 2015