Anti-BNP/ProBNP antibody - C-terminal (ab196343)

Overview

  • Product name
    Anti-BNP/ProBNP antibody - C-terminal
    See all BNP/ProBNP primary antibodies
  • Description
    Rabbit polyclonal to BNP/ProBNP - C-terminal
  • Tested applications
    Suitable for: ICC, WB, ELISA, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Non human primates
  • Immunogen

    Synthetic peptide corresponding to Human BNP/ProBNP (C terminal).
    Database link: P16860

Properties

Applications

Our Abpromise guarantee covers the use of ab196343 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC 1/200 - 1/1000.
WB 1/500 - 1/2000. Predicted molecular weight: 15 kDa.
ELISA Use at an assay dependent concentration.
ICC/IF 1/200 - 1/1000.

Target

  • Function
    Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • Tissue specificity
    Brain and also in atria, but at much lower levels than ANP.
  • Sequence similarities
    Belongs to the natriuretic peptide family.
  • Post-translational
    modifications
    The brain natriuretic peptide 32 form is cleaved at Pro-104 by the prolyl endopeptidase FAP (seprase) activity (in vitro).
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • ANFB_HUMAN antibody
    • BNP antibody
    • BNP(1-32) antibody
    • BNP(5-29) antibody
    • BNP-32 antibody
    • Brain type natriuretic peptide antibody
    • Gamma brain natriuretic peptide antibody
    • Gamma-brain natriuretic peptide antibody
    • Natriuretic peptide B antibody
    • Natriuretic peptide precursor B antibody
    • Natriuretic protein antibody
    • nppb antibody
    see all

References

ab196343 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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