Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA).
Use at an assay dependent dilution. Preliminary experiments gave an approx 37kDa currently we cannot find an explanation in the literature for the band we observe given the calculated size of 19.2kDa according to NP_612378.1.
FunctionRequired for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles.
Sequence similaritiesBelongs to the BOD1 family.
Cellular localizationCytoplasm > cytoskeleton > centrosome. Chromosome > centromere > kinetochore. Localizes at the centrosomes throughout the cell cycle, only dissociating during cytokinesis. Localizes at the kinetochore from prometaphase until anaphase.