Overview

  • Product name
    Anti-Bombesin antibody
  • Description
    Rabbit polyclonal to Bombesin
  • Specificity
    Absorption with Bombesin at 10-100µg/ml of diluted antiserum abolishes the staining.
  • Tested applications
    Suitable for: IHC-Fr, IHC-Pmore details
  • Species reactivity
    Reacts with: Rat, Chicken, Human
  • Immunogen

    Full length protein corresponding to Bombesin conjugated to Bovine Serum Albumin (BSA). Amphibian

  • Positive control
    • Rat or Chicken stomach

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: Whole serum
  • Purity
    Whole antiserum
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab86037 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/400 - 1/800.
IHC-P 1/400 - 1/800.

Target

  • Relevance
    Bombesin is a 14 amino acid peptide originally isolated from the skin of a frog. It has two known homologues in mammals called neuromedin B and gastrin releasing peptide. It works on the gastrointestinal tract neuroendocrine hormone and it stimulates gastrin release from G cells. It activates three different G-protein coupled receptors known as BBR1 2 & 3. It also activates these receptors in the brain. Together with cholecystokinin it is the second major source of negative feedback signals that stop eating behaviour. There are three different isoforms.
  • Cellular localization
    Secreted
  • Database links
  • Alternative names
    • BN antibody
    • Gastric releasing peptide antibody
    • Gastrin releasing peptide antibody
    • GRP 10 antibody
    • GRP antibody
    • GRP10 antibody
    • Neuromedin C antibody
    • NeuromedinC antibody
    • Pre progastrin releasing peptide antibody
    • PreproGRP antibody
    • ProGRP antibody
    see all

References

This product has been referenced in:
  • Singh SP  et al. HIF-1a Plays a Critical Role in the Gestational Sidestream Smoke-Induced Bronchopulmonary Dysplasia in Mice. PLoS One 10:e0137757 (2015). IHC-P, WB ; Mouse . Read more (PubMed: 26361040) »

See 1 Publication for this product

Customer reviews and Q&As

Thank you for your phone call.
The database entry for the mouse NFkB protein is as follows:
http://www.uniprot.org/uniprot/Q04207
There, you will find the list of potential phosporylation sites, their kinases as well as references.
...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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