The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use 10µl for 106 cells. (Volume of 100µl)
ab37391-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
FunctionSynthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.
Tissue specificityWidely expressed.
Sequence similaritiesBelongs to the ADP-ribosyl cyclase family.