Anti-CXCR6 antibody (ab125115)
Key features and details
- Goat polyclonal to CXCR6
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CXCR6 antibody
See all CXCR6 primary antibodies -
Description
Goat polyclonal to CXCR6 -
Host species
Goat -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Dog -
Immunogen
Synthetic peptide:
SEDNSKTFSASHN
with a Cysteine residue linker, corresponding to C terminal amino acids 321-333 of Human Bonzo (NP_006555.1). -
Positive control
- Human thymus tissue; HEK293 lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 99% Tris buffered saline -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab125115 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 39 kDa.
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IHC-P |
Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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WB
Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 39 kDa. |
IHC-P
Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. -
Tissue specificity
Expressed in lymphoid tissues and activated T cells. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 10663 Human
- Entrez Gene: 80901 Mouse
- Entrez Gene: 100124593 Rat
- Omim: 605163 Human
- SwissProt: O00574 Human
- SwissProt: Q9EQ16 Mouse
- Unigene: 34526 Human
- Unigene: 124289 Mouse
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Alternative names
- bonzo antibody
- C X C chemokine receptor type 6 antibody
- C-X-C chemokine receptor type 6 antibody
see all
Images
Protocols
Datasheets and documents
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Datasheet download
References (2)
ab125115 has been referenced in 2 publications.
- Hald SM et al. Prognostic impact of CXCL16 and CXCR6 in non-small cell lung cancer: combined high CXCL16 expression in tumor stroma and cancer cells yields improved survival. BMC Cancer 15:441 (2015). IHC . PubMed: 26021984
- Richardsen E et al. The prognostic significance of CXCL16 and its receptor C-X-C chemokine receptor 6 in prostate cancer. Am J Pathol 185:2722-30 (2015). PubMed: 26272362