Anti-Bordetella pertussis toxin subunit S2 antibody [20.6] (ab27158)

Overview

  • Product name
    Anti-Bordetella pertussis toxin subunit S2 antibody [20.6]
  • Description
    Mouse monoclonal [20.6] to Bordetella pertussis toxin subunit S2
  • Specificity
    Reacts with the intact toxin as well as the S2 subunit. Some reactivity towards the toxoid is also present.
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with Bordetella pertussis. Not yet tested in other species.
  • Immunogen

    Pertussis Toxin.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C.
  • Storage buffer
    Preservative: None
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4.
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Monoclonal
  • Clone number
    20.6
  • Myeloma
    x63-Ag8.653
  • Isotype
    IgG1
  • Light chain type
    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab27158 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/100000.
WB 1/1000.

Target

  • Relevance
    Pertussis toxin (islet activating protein) is the major protein toxin produced by virulent strains of Bordetella pertussis. As revealed by polyacrylamide gel electrophoresis, the purified protein consists of five dissimilar subunits: S1 (MW 28,000), S2 (MW 23,000), S3 (MW 22,000), S4 (MW 11,700) and S5 (MW 9,300), in a molar ratio of 1:1:1:2:1. The A protomer, S1 is responsible for the enzymatic activity of the toxin. Together, S2, S3, S4 and S5 comprise the B oligomer, responsible for binding the toxin to the cell surface.
  • Alternative names
    • B.pertussis S2 antibody
    • B.pertussis toxin subunit S2 antibody
    • Bordetella pertussis S2 antibody
    • IAP S2 antibody
    • Islet activating protein S2 antibody
    • Pertussis toxin S2 antibody
    • Pertussis toxin subunit 2 antibody
    • Ptx B antibody
    • PTX S2 antibody
    • PtxB antibody
    see all

References for Anti-Bordetella pertussis toxin subunit S2 antibody [20.6] (ab27158)

This product has been referenced in:
  • Ibsen PH The effect of formaldehyde, hydrogen peroxide and genetic detoxification of pertussis toxin on epitope recognition by murine monoclonal antibodies. Vaccine 14:359-68 (1996). Read more (PubMed: 8735545) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab27158.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up