Anti-Bordetella pertussis toxin subunit S2 antibody [20.6] (ab27158)

Overview

  • Product nameAnti-Bordetella pertussis toxin subunit S2 antibody [20.6]
  • Description
    Mouse monoclonal [20.6] to Bordetella pertussis toxin subunit S2
  • SpecificityReacts with the intact toxin as well as the S2 subunit. Some reactivity towards the toxoid is also present.
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with Bordetella pertussis. Not yet tested in other species.
  • Immunogen

    Pertussis Toxin.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferPreservative: None
    Constituents: 0.5M Sodium chloride, 0.01M PBS, pH 7.4.
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • Clone number20.6
  • Myelomax63-Ag8.653
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab27158 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/100000.
WB 1/1000.

Target

  • RelevancePertussis toxin (islet activating protein) is the major protein toxin produced by virulent strains of Bordetella pertussis. As revealed by polyacrylamide gel electrophoresis, the purified protein consists of five dissimilar subunits: S1 (MW 28,000), S2 (MW 23,000), S3 (MW 22,000), S4 (MW 11,700) and S5 (MW 9,300), in a molar ratio of 1:1:1:2:1. The A protomer, S1 is responsible for the enzymatic activity of the toxin. Together, S2, S3, S4 and S5 comprise the B oligomer, responsible for binding the toxin to the cell surface.
  • Alternative names
    • B.pertussis S2 antibody
    • B.pertussis toxin subunit S2 antibody
    • Bordetella pertussis S2 antibody
    • IAP S2 antibody
    • Islet activating protein S2 antibody
    • Pertussis toxin S2 antibody
    • Pertussis toxin subunit 2 antibody
    • Ptx B antibody
    • PTX S2 antibody
    • PtxB antibody
    see all

References for Anti-Bordetella pertussis toxin subunit S2 antibody [20.6] (ab27158)

This product has been referenced in:
  • Ibsen PH The effect of formaldehyde, hydrogen peroxide and genetic detoxification of pertussis toxin on epitope recognition by murine monoclonal antibodies. Vaccine 14:359-68 (1996). Read more (PubMed: 8735545) »
  • Ibsen PH The effect of formaldehyde, hydrogen peroxide and genetic detoxification of pertussis toxin on epitope recognition by murine monoclonal antibodies. Vaccine 14:359-68 (1996). Read more (PubMed: 8735545) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"