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Storage instructions Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
Concentration information loading...
Purity Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 30 kDa.
1/100 - 1/200.
Function Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 18.104.22.168) and phosphatase (EC 22.214.171.124) activities.
Involvement in disease Defects in BPGM are the cause of bisphosphoglycerate mutase deficiency (BPGMD) [MIM:222800]. A disease characterized by hemolytic anemia, splenomegaly, cholelithiasis and cholecystitis.
Sequence similarities Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Post-translational modifications Glycation of Lys-159 in diabetic patients inactivates the enzyme.
Information by UniProt
2,3-bisphosphoglycerate mutase antibody
2,3-bisphosphoglycerate mutase, erythrocyte antibody
Anti-BPGM antibody images
Western blot - BPGM antibody (ab97497)
All lanes : Anti-BPGM antibody (ab97497) at 1/1000 dilution Lane 1 : 293T whole cell lysate Lane 2 : A431 whole cell lysate Lane 3 : H1299 whole cell lysate Lysates/proteins at 30 µg per lane. Predicted band size : 30 kDa
Immunocytochemistry/ Immunofluorescence - BPGM antibody (ab97497)
ab97497, at 1/100 dilution, staining BPGM in paraformaldehyde-fixed HeLa cells by Immunofluorescence. Lower image is merged with DNA probe.
References for Anti-BPGM antibody (ab97497)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"