Overview

  • Product name
  • Description
    Rabbit polyclonal to BRAP
  • Tested applications
    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chicken, Cow, Dog, Turkey, Chimpanzee, Rhesus monkey, Opossum, Orangutan, Bat
  • Immunogen

    Immunogen corresponds to a region between residue 510 and 560 (EEERVLKETC DQKDLQITEI QEQLRDVMFY LETQQKINHL PAETRQEIQE G) of Human BRAP using the numbering given in entry NP_006759.3

  • Positive control
    • HeLa whole cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab95179 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-5 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Relevance
      BRCA1 Associated Protein, BRAP2 (Impedes mitogenic signal propogation; IMP) is mainly cytoplasmic and binds to the NLS motifs of BRCA1 with similar specificity to that of importin alpha. BRAP2 may function as a cytoplasmic retention protein and play a role in regulating transport of nuclear proteins. More recently, the protein has been shown to impede signal transmission from Raf to MEK.
    • Cellular localization
      Cytoplasmic
    • Database links
    • Alternative names
      • 3010002G07Rik antibody
      • BRAP2 antibody
      • BRCA1 associated protein antibody
      • EC 6.3.2. antibody
      • Galectin 2 binding protein antibody
      • IMP antibody
      • Impedes mitogenic signal propagation antibody
      • Renal carcinoma antigen NY REN 63 antibody
      • RING finger protein 52 antibody
      • RNF52 antibody
      • zgc:92894 antibody
      see all

    Images

    • 3µg/ml ab95179 were used to immunoprecipitate BRAP from 1mg HeLa whole cell lysate.
      20% IP was loaded and probed with a different BRAP-specific antibody.
      Detection: chemiluminescence with exposure time of 30 seconds.

    References

    ab95179 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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